Relationship of body fat distribution by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance by homeostasis model assessment and lipid profile in obese and non-obese postmenopausal women (2005)
- Authors:
- Autor USP: ALDRIGHI, JOSE MENDES - FSP
- Unidade: FSP
- DOI: 10.1080/09513590500361937
- Subjects: OBESIDADE; MENOPAUSA; CONSTITUIÇÃO CORPORAL; HORMÔNIOS DO PÂNCREAS ENDÓCRINO (RESISTÊNCIA); FISIOLOGIA (PROCESSOS)
- Language: Inglês
- Abstract: Objective: To correlate body fat distribution evaluated by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance and lipid profile in obese and non-obese postmenopausal women. Methods. We studied 40 obese and 47 non-obese postmenopausal women, assessing obesity by measuring waist circumference and fat tissue using dual-energy X-ray absorptiometry and ultrasonography, and examining their correlation with metabolic parameters: insulin resistance as determined by the homeostasis model assessment technique (HOMA-IR) and lipid profile including triglycerides (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), very-low-density lipoprotein, lipoprotein(a) (Lp(a)) and apoplipoprotein A-I (Apo A-I). Results. There was no difference in lipid profile between the two groups. Insulin resistance was the metabolic disturbance of highest prevalence in the obese group, evaluated by HOMA-IR (obese: 3.38 ± 2.2; non-obese: 1.20 ± 0.7; p < 0.001). Obesity was not a confounding factor in linear regression analyses among HOMA-IR, HDL-C, TG, Lp(a), Apo A-I and the methods used to measure body fat distribution. Waist circumference was the method that best explained HOMA-IR (R2 = 34.9 percent, p < 0.001) and TG concentration (R2 = 10.9 percent, p = 0.002). HDL-C presented a positive association with subcutaneous fat evaluated by ultrasonography (R2 = 12.5 percent, p < 0.001).Obesity was a confounding factor in multiple regression analyses between TC and LDL-C, when related to abdominal fat evaluated by ultrasonography, and resulted in a positive association among the obese and a negative association among the non-obese women. The sensibility of this method was related to the quantity of fat in the visceral region. ) Conclusions. Waist circumference showed the highest association with insulin resistance. Fat distribution evaluated by dual-energy X-ray absorptiometry and ultrasound was also associated with insulin resistance, but with lower intensity. The relationship of visceral fat distribution evaluated by ultrasound to TC cholesterol and LDL-C showed opposed results between obese and non-obese menopausal women
- Imprenta:
- Source:
- Título do periódico: Gynecological endocrinology
- ISSN: 0951-3590
- Volume/Número/Paginação/Ano: v. 21, n. 5, p. 295-301, 2005
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
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ABNT
SANTOS, Roberto Euzebio dos et al. Relationship of body fat distribution by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance by homeostasis model assessment and lipid profile in obese and non-obese postmenopausal women. Gynecological endocrinology, v. 21, n. 5, p. 295-301, 2005Tradução . . Disponível em: https://doi.org/10.1080/09513590500361937. Acesso em: 16 maio 2024. -
APA
Santos, R. E. dos, Aldrighi, J. M., Lanz, J. R., Ferezin, P. C., & Marone, M. M. S. (2005). Relationship of body fat distribution by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance by homeostasis model assessment and lipid profile in obese and non-obese postmenopausal women. Gynecological endocrinology, 21( 5), 295-301. doi:10.1080/09513590500361937 -
NLM
Santos RE dos, Aldrighi JM, Lanz JR, Ferezin PC, Marone MMS. Relationship of body fat distribution by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance by homeostasis model assessment and lipid profile in obese and non-obese postmenopausal women [Internet]. Gynecological endocrinology. 2005 ; 21( 5): 295-301.[citado 2024 maio 16 ] Available from: https://doi.org/10.1080/09513590500361937 -
Vancouver
Santos RE dos, Aldrighi JM, Lanz JR, Ferezin PC, Marone MMS. Relationship of body fat distribution by waist circumference, dual-energy X-ray absorptiometry and ultrasonography to insulin resistance by homeostasis model assessment and lipid profile in obese and non-obese postmenopausal women [Internet]. Gynecological endocrinology. 2005 ; 21( 5): 295-301.[citado 2024 maio 16 ] Available from: https://doi.org/10.1080/09513590500361937 - Comparison between raloxifene and hormone replacement therapy on ambulatory blood pressure and arterial stiffness
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Informações sobre o DOI: 10.1080/09513590500361937 (Fonte: oaDOI API)
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