Artigo de periodico

Age at natural menopause and mortality: a survival analysis of elderly residents of São Paulo, Brazil (2018)

• Authors:
  • Lay, Alejandra Andrea Roman
  • Nascimento, Carla Ferreira do
  • Duarte, Yeda Aparecida de Oliveira
  • Chiavegatto Filho, Alexandre Dias Porto
• USP affiliated authors: DUARTE, YEDA APARECIDA DE OLIVEIRA - EE ; CHIAVEGATTO FILHO, ALEXANDRE DIAS PORTO - FSP ; LAY, ALEJANDRA ANDREA ROMÁN - FSP ; NASCIMENTO, CARLA FERREIRA DO - FSP
• Unidades: EE; FSP
• DOI: 10.1016/j.maturitas.2018.08.012
• Subjects: ENVELHECIMENTO; DOENÇAS CARDIOVASCULARES; DOENÇAS RESPIRATÓRIAS; NEOPLASIAS; MORTALIDADE; MENOPAUSA
• Agências de fomento:
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
    Processo FAPESP: 09/53778-3
• Language: Inglês
• Abstract: Objective:To conduct a survival analysis according to age at natural menopause (NM) in a representative sampleof elderly women from the municipality of São Paulo, Brazil.Study design:We analyzed data from the Health, Well-Being and Aging study (SABE), a cohort that started in2000. Mortality data up to September 2016 were obtained by linkage from the Program for MortalityInformation of São Paulo (PRO-AIM).Main outcome measures:We used Cox regression to analyze all-cause and cause-specific mortality rates forcardiovascular diseases, respiratory diseases and cancer, according to age at menopause, categorized as < 40,41–44, 45–49, 50–54 (reference) and≥55.Results:After 16 years of follow-up, there were 444 deaths, of which 199 were from cardiovascular diseases, 73from respiratory diseases and 65 from cancer. After adjustment for socioeconomic, reproductive and lifestylefactors, having an early menopause (at age 41–44) was associated with an increased risk of all-cause mortality(HR = 1.48, 95% IC: 1.03, 2.14) relative to NM at 50–54 years. Women aged 41–44 and 45–49 at NM had twicethe risk of cancer mortality of the reference group. We did notfind significant associations between age at NMand cause-specific mortality for respiratory and cardiovascular diseases.Conclusions:Ourfindings suggest that early menopause is associated with all-cause mortality in the largest cityof Latin America. In addition, earlier age at NM was associated with cancer mortality. These results suggest thatage at NM may be a biomarker for mortality, irrespective of country of residence
• Imprenta:
  • Publisher place: Limerick
  • Date published: 2018
• Source:
  • Título do periódico: Maturitas
  • ISSN: 0378-5122
  • Volume/Número/Paginação/Ano: v.117, p. 29-33, 2018

Informações sobre o DOI: 10.1016/j.maturitas.2018.08.012 (Fonte: oaDOI API)
• Este periódico é de assinatura
• Este artigo NÃO é de acesso aberto
  
• Cor do Acesso Aberto: closed

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How to cite

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• ABNT

  LAY, Alejandra Andrea Roman et al. Age at natural menopause and mortality: a survival analysis of elderly residents of São Paulo, Brazil. Maturitas, v. 117, p. 29-33, 2018Tradução . . Disponível em: https://doi.org/10.1016/j.maturitas.2018.08.012. Acesso em: 10 maio 2024.

• APA

  Lay, A. A. R., Nascimento, C. F. do, Duarte, Y. A. de O., & Chiavegatto Filho, A. D. P. (2018). Age at natural menopause and mortality: a survival analysis of elderly residents of São Paulo, Brazil. Maturitas, 117, 29-33. doi:10.1016/j.maturitas.2018.08.012

• NLM

  Lay AAR, Nascimento CF do, Duarte YA de O, Chiavegatto Filho ADP. Age at natural menopause and mortality: a survival analysis of elderly residents of São Paulo, Brazil [Internet]. Maturitas. 2018 ;117 29-33.[citado 2024 maio 10 ] Available from: https://doi.org/10.1016/j.maturitas.2018.08.012

• Vancouver

  Lay AAR, Nascimento CF do, Duarte YA de O, Chiavegatto Filho ADP. Age at natural menopause and mortality: a survival analysis of elderly residents of São Paulo, Brazil [Internet]. Maturitas. 2018 ;117 29-33.[citado 2024 maio 10 ] Available from: https://doi.org/10.1016/j.maturitas.2018.08.012

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