SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy (2019)
- Authors:
- USP affiliated authors: QUEIROZ, ANDRÉ LIMA - FMRP ; SOUSA, LUCAS OLIVEIRA - FCFRP ; UYEMURA, SERGIO AKIRA - FCFRP ; CURTI, CARLOS - FCFRP ; LEOPOLDINO, ANDRÉIA MACHADO - FCFRP ; BRAUER, VERÔNICA SOARES - FMRP
- Unidades: FMRP; FCFRP
- DOI: 10.1016/j.bbamcr.2019.01.005
- Subjects: DEGRANULAÇÃO CELULAR; CARCINOMA DE CÉLULAS ESCAMOSAS; CABEÇA; PESCOÇO; ESTRESSE OXIDATIVO
- Keywords: Autophagy; Cell death; Head and neck squamous cell carcinoma; Oxidative stress; SET protein
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título do periódico: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- ISSN: 0167-4889
- Volume/Número/Paginação/Ano: v. 1866, n. 4, p. 623-637, 2019
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
OUCHIDA, Amanda Tomie et al. SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, v. 1866, n. 4, p. 623-637, 2019Tradução . . Disponível em: https://doi.org/10.1016/j.bbamcr.2019.01.005. Acesso em: 30 abr. 2024. -
APA
Ouchida, A. T., Uyemura, V. T., Queiroz, A. L., Brauer, V. S., Cavalcanti Neto, M. P., Sousa, L. O., et al. (2019). SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1866( 4), 623-637. doi:10.1016/j.bbamcr.2019.01.005 -
NLM
Ouchida AT, Uyemura VT, Queiroz AL, Brauer VS, Cavalcanti Neto MP, Sousa LO, Uyemura SA, Curti C, Leopoldino AM. SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy [Internet]. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2019 ; 1866( 4): 623-637.[citado 2024 abr. 30 ] Available from: https://doi.org/10.1016/j.bbamcr.2019.01.005 -
Vancouver
Ouchida AT, Uyemura VT, Queiroz AL, Brauer VS, Cavalcanti Neto MP, Sousa LO, Uyemura SA, Curti C, Leopoldino AM. SET protein accumulation prevents cell death in head and neck squamous cell carcinoma through regulation of redox state and autophagy [Internet]. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2019 ; 1866( 4): 623-637.[citado 2024 abr. 30 ] Available from: https://doi.org/10.1016/j.bbamcr.2019.01.005 - SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation
- SET overexpression in HEK293 cells regulates mitochondrial uncoupling proteins levels within a mitochondrial fission/reduced autophagic flux scenario
- SET overexpression decreases cell detoxification efficiency: ALDH2 and GSTP1 are dowregulated, DDR is impaired and DNA damage accumulates
- Vias alternativas mitocondriais: estudos da NADH desidrogenase alternativa externa de Aspergillus fumigatus
- SET/I2PP2A protein accumulation and ethanol detoxification: decrease of the ALDH2 levels and failure in DNA damage repair mechanism
- Evidence for involvement of SET/I2PP2A on cancer resistance to apoptosis induced by oxidative stress
- The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler
- SET/I2PP2A is an essential protein for cell migration in head and neck squamous cell carcinoma
- SET protects mitochondria from apoptosis signaling and favors autophagy in HNSCC cells exposed to a pro-oxidant
- Epigenetic regulation by SET protein in HNSCC: histone acetylation versus DNA methylation
Informações sobre o DOI: 10.1016/j.bbamcr.2019.01.005 (Fonte: oaDOI API)
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