Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects (2019)
- Authors:
- USP affiliated authors: AMARAL, JEFFERSON HENRICH - FMRP ; TELLA, SANDRA DE OLIVEIRA CONDE - FMRP ; PINHEIRO, LUCAS CÉZAR - EERP ; GERLACH, RAQUEL FERNANDA - FORP ; CASTRO, MICHELE MAZZARON DE - FMRP ; SANTOS, JOSE EDUARDO TANUS DOS - FMRP ; GUIMARÃES, DANIELLE APARECIDA - FMRP
- Unidades: FMRP; EERP; FORP
- DOI: 10.1016/j.freeradbiomed.2018.11.002
- Subjects: NITRITOS; ESTRESSE OXIDATIVO; HIPERTENSÃO
- Keywords: Nitrite; Oxidative stress; MMP-2; Vascular remodeling; Hypertension
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher place: Philadelphia
- Date published: 2019
- Source:
- Título do periódico: Free Radical Biology and Medicine
- ISSN: 0891-5849
- Volume/Número/Paginação/Ano: v. 130, p. 234-243, 2019
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: hybrid
- Licença: publisher-specific-oa
-
ABNT
RIZZI, Elen et al. Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects. Free Radical Biology and Medicine, v. 130, p. 234-243, 2019Tradução . . Disponível em: https://doi.org/10.1016/j.freeradbiomed.2018.11.002. Acesso em: 30 abr. 2024. -
APA
Rizzi, E., Amaral, J. H., Guimarães, D. A., Conde-Tella, S. de O., Pinheiro, L. C., Gerlach, R. F., et al. (2019). Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects. Free Radical Biology and Medicine, 130, 234-243. doi:10.1016/j.freeradbiomed.2018.11.002 -
NLM
Rizzi E, Amaral JH, Guimarães DA, Conde-Tella S de O, Pinheiro LC, Gerlach RF, Castro MM de, Tanus-Santos JE. Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects [Internet]. Free Radical Biology and Medicine. 2019 ; 130 234-243.[citado 2024 abr. 30 ] Available from: https://doi.org/10.1016/j.freeradbiomed.2018.11.002 -
Vancouver
Rizzi E, Amaral JH, Guimarães DA, Conde-Tella S de O, Pinheiro LC, Gerlach RF, Castro MM de, Tanus-Santos JE. Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects [Internet]. Free Radical Biology and Medicine. 2019 ; 130 234-243.[citado 2024 abr. 30 ] Available from: https://doi.org/10.1016/j.freeradbiomed.2018.11.002 - Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy
- Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway
- Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect
- Tempol improves xanthine oxidoreductase-mediated vascular responses to nitrite in experimental renovascular hypertension
- The potential of stimulating nitric oxide formation in the treatment of hypertension
- Matrix metalloproteinase (MMP)-2 decreases calponin-1 levels and contributes to arterial remodeling in early hypertension
- Imbalance between matrix metalloproteinase (MMP)-2 and calponin-1 in early hypertensive vascular remodeling
- Targeting matrix metalloproteinases in disease conditions. [Editorial]
- Hemodynamic benefits of matrix metalloproteinase-9 inhibition by doxycycline during experimental acute pulmonary embolism
- Inibição de metaloproteinases (MMPs) com Doxycycline atenua a embolia pulmonar aguda (EPA)-indutor de hipotensão sistêmica
Informações sobre o DOI: 10.1016/j.freeradbiomed.2018.11.002 (Fonte: oaDOI API)
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