Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate (2022)
- Authors:
- Freire, Marjorie Caroline Liberato Cavalcanti
- Basso, Luís Guilherme Mansor
- Mendes, Luis Felipe Santos
- Mesquita, Nathalya Cristina de Moraes Roso
- Mottin, Melina - Universidade Federal de Goiás (UFG)
- Fernandes, Rafaela Sachetto
- Policastro, Lucca Rocha
- Godoy, Andre Schutzer de
- Santos, Igor A. - Universidade Federal de Uberlândia (UFU)
- Ruiz, Uriel Enrique Aquino - Universidade Federal de Uberlândia (UFU)
- Caruso, Icaro P. - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
- Sousa, Bruna K. P. - Universidade Federal de Goiás (UFG)
- Jardim, Ana C. G. - Universidade Federal de Uberlândia (UFU)
- Almeida, Fabio C. L. - Universidade Federal do Rio de Janeiro (UFRJ)
- Gil, Laura Helena Vega Gonzales
- Andrade, Carolina H. - Universidade Federal de Goiás (UFG)
- Oliva, Glaucius
- USP affiliated authors: OLIVA, GLAUCIUS - IFSC ; FREIRE, MARJORIE CAROLINE LIBERATO CAVALCANTI - IFSC ; MENDES, LUIS FELIPE SANTOS - FFCLRP ; MESQUITA, NATHALYA CRISTINA DE MORAES ROSO - IFSC ; FERNANDES, RAFAELA SACHETTO - IFSC ; GODOY, ANDRE SCHÜTZER DE - IFSC
- Unidades: IFSC; FFCLRP
- DOI: 10.1038/s41598-022-14790-x
- Subjects: VÍRUS CHIKUNGUNYA; ESTRUTURA MOLECULAR (QUÍMICA TEÓRICA); QUÍMICA MÉDICA; RNA
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título do periódico: Scientific Reports
- ISSN: 2045-2322
- Volume/Número/Paginação/Ano: v. 12, p. 10601-1-10601-15, June 2022
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
FREIRE, Marjorie Caroline Liberato Cavalcanti et al. Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate. Scientific Reports, v. 12, p. 10601-1-10601-15, 2022Tradução . . Disponível em: https://doi.org/10.1038/s41598-022-14790-x. Acesso em: 15 maio 2024. -
APA
Freire, M. C. L. C., Basso, L. G. M., Mendes, L. F. S., Mesquita, N. C. de M. R., Mottin, M., Fernandes, R. S., et al. (2022). Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate. Scientific Reports, 12, 10601-1-10601-15. doi:10.1038/s41598-022-14790-x -
NLM
Freire MCLC, Basso LGM, Mendes LFS, Mesquita NC de MR, Mottin M, Fernandes RS, Policastro LR, Godoy AS de, Santos IA, Ruiz UEA, Caruso IP, Sousa BKP, Jardim ACG, Almeida FCL, Gil LHVG, Andrade CH, Oliva G. Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate [Internet]. Scientific Reports. 2022 ; 12 10601-1-10601-15.[citado 2024 maio 15 ] Available from: https://doi.org/10.1038/s41598-022-14790-x -
Vancouver
Freire MCLC, Basso LGM, Mendes LFS, Mesquita NC de MR, Mottin M, Fernandes RS, Policastro LR, Godoy AS de, Santos IA, Ruiz UEA, Caruso IP, Sousa BKP, Jardim ACG, Almeida FCL, Gil LHVG, Andrade CH, Oliva G. Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate [Internet]. Scientific Reports. 2022 ; 12 10601-1-10601-15.[citado 2024 maio 15 ] Available from: https://doi.org/10.1038/s41598-022-14790-x - Imidazonaphthyridine effects on Chikungunya virus replication: antiviral activity by dependent and independent of interferon type 1 pathways
- Biophysical characterization of the RNA-dependent RNA polimerase (nsP4) protein of Chikungunya virus
- Insights into the role of the cobalt(III)-thiosemicarbazone complex as a potential inhibitor of the Chikungunya virus nsP4
- The protein disulfide isomerase inhibitor 3-methyltoxoflavin inhibits Chikungunya virus
- Reporter replicon systems for the screening of potential antiviral agents against zika, yellow fever and chikungunya viruses
- The Antifungal itraconazole is a potent inhibitor of Chikungunya virus replication
- Naphthyridine-derived compound effectively inhibits the early stages of CHIKV virus infection in vitro
- Reporter replicons for antiviral drug discovery against positive single-stranded RNA viruses
- Identification of Zika virus NS2B-NS3 protease inhibitors through a high-throughput fluorescence-based assay
- Structural and biochemical characterization of SARS-CoV-2 main protease maturation process
Informações sobre o DOI: 10.1038/s41598-022-14790-x (Fonte: oaDOI API)
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