Scaling up xylitol bioproduction: Challenges to achieve a profitable bioprocess (2022)
- Authors:
- USP affiliated authors: FELIPE, MARIA DAS GRAÇAS DE ALMEIDA - EEL ; QUEIROZ, SARAH DE SOUZA - EEL ; JOFRE, FANNY MACHADO - EEL
- Unidade: EEL
- DOI: 10.1016/j.rser.2021.111789
- Assunto: BIOTECNOLOGIA
- Keywords: Techno-economic analysis; Scaling up; Xylitol; Adaptive evolution; Strain development
- Agências de fomento:
- Language: Inglês
- Abstract: Xylitol is a GRAS (Generally Recognized as Safe) polyol commonly used in the food industry and able to promote several benefits to the health. In addition, it can also be used as a building block molecule for the manufacture of different high-value chemicals. Currently, the commercial production of xylitol occurs by chemical route through the catalytic hydrogenation of xylose from lignocellulosic biomass. Since this is an expensive process due to the severe reactional conditions employed, the biotechnological route for xylitol production, which comprises the biological conversion of xylose into xylitol, emerges as a potential lower-cost alternative to obtain this polyol due to the milder process conditions required. However, the biotechnological route still presents important bottlenecks and challenges that impairs the process scaling up. Modern strategies and technologies that can potentially improve xylitol bioproduction include adaptive evolution of microbial strains to enhance their tolerance to inhibitors and the xylose uptake rate during the fermentation step; development of engineered microorganisms to result in higher xylose-to-xylitol bioconversion yields; as well as xylitol purification techniques to improve the recovery yields. Moreover, techno-economic analysis of the overall production chain is essential to identify the process viability for large-scale implementation as well as the steps requiring improvements. These are some key factors discussed in this review, which aims to provide insights for the development of a more economically competitive, less energy demanding and scalable new technology for xylitol production.
- Imprenta:
- Publisher place: Kongens Lyngby
- Date published: 2022
- Source:
- Título do periódico: Renewable & sustainable energy reviews
- ISSN: 13640321
- Volume/Número/Paginação/Ano: v., n. , p.111789-, 2022
- Este periódico é de assinatura
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: hybrid
- Licença: cc-by
-
ABNT
QUEIROZ, Sarah de Souza et al. Scaling up xylitol bioproduction: Challenges to achieve a profitable bioprocess. Renewable & sustainable energy reviews, n. , p. 111789-, 2022Tradução . . Disponível em: https://doi.org/10.1016/j.rser.2021.111789. Acesso em: 01 maio 2024. -
APA
Queiroz, S. de S., Jofre, F. M., Mussatto, S. I., & Felipe, M. das G. de A. (2022). Scaling up xylitol bioproduction: Challenges to achieve a profitable bioprocess. Renewable & sustainable energy reviews, ( ), 111789-. doi:10.1016/j.rser.2021.111789 -
NLM
Queiroz S de S, Jofre FM, Mussatto SI, Felipe M das G de A. Scaling up xylitol bioproduction: Challenges to achieve a profitable bioprocess [Internet]. Renewable & sustainable energy reviews. 2022 ;( ): 111789-.[citado 2024 maio 01 ] Available from: https://doi.org/10.1016/j.rser.2021.111789 -
Vancouver
Queiroz S de S, Jofre FM, Mussatto SI, Felipe M das G de A. Scaling up xylitol bioproduction: Challenges to achieve a profitable bioprocess [Internet]. Renewable & sustainable energy reviews. 2022 ;( ): 111789-.[citado 2024 maio 01 ] Available from: https://doi.org/10.1016/j.rser.2021.111789 - Potential use of the dried biomass of Candida guilliermondii FTI20037 in the context of a sugarcane biorefinery
- Relation of xylitol formation and lignocellulose degradation in yeast
- Biotechnological production of sweeteners
- Introduction of a biodegradable agent for detoxification of hemicellulosic hydrolysates for xylitol production
- Yeast biomass as biotechnological strategy for detoxification of hemicellulosic hydrolysate of sugarcane byproducts for xylitol production
- Fermentative Production of Xylitol from Various Lignocellulosic Hydrolysates
- Obtencao de xilitol por fermentacao do hidrolisado hemicelulosico de bagaco de cana-de-acucar
- Xylitol bioproduction in hemicellulosic hydrolysate obtained from sorghum forage biomass
- Valorization of apple pomace using bio-based technology for the production of xylitol and 2G ethanol
- Integrated bioinformatics, modelling, and gene expression analysis of the putative pentose transporter from Candida tropicalis during xylose fermentation with and without glucose addition
Informações sobre o DOI: 10.1016/j.rser.2021.111789 (Fonte: oaDOI API)
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas
