Design and synthesis of new potential PI3K and HDAC6 hybrid inhibitors for cancer treatment (2023)
- Authors:
- USP affiliated authors: TOLEDO, MONICA FRANCO ZANNINI JUNQUEIRA - FCF ; LOTUFO, LETICIA VERAS COSTA - ICB ; MACHADO NETO, JOÃO AGOSTINHO - ICB ; PARISE FILHO, ROBERTO - FCF ; WAITMAN, KAROLINE DE BARROS - FCF ; ALMEIDA, LARISSA COSTA DE - ICB ; CARLOS, JORGE ANTONIO ELIAS GODOY - ICB
- Unidades: FCF; ICB
- Subjects: NEOPLASIAS; HIBRIDIZAÇÃO
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Publisher: Sociedade Brasileira de Química/SBQ
- Publisher place: São Paulo
- Date published: 2023
- Source:
- Título do periódico: Anais
- Conference titles: Reunião Anual da Sociedade Brasileira de Química/RASBQ
-
ABNT
WAITMAN, Karoline de Barros et al. Design and synthesis of new potential PI3K and HDAC6 hybrid inhibitors for cancer treatment. 2023, Anais.. São Paulo: Sociedade Brasileira de Química/SBQ, 2023. Disponível em: https://www.sbq.org.br/46ra/anexos/anais-46rasbq.pdf. Acesso em: 30 abr. 2024. -
APA
Waitman, K. de B., Tavares, M. T., Almeida, L. C. de, Carlos, J. A. E. G., Kronenberger, T., Toledo, M. F. Z. J., et al. (2023). Design and synthesis of new potential PI3K and HDAC6 hybrid inhibitors for cancer treatment. In Anais. São Paulo: Sociedade Brasileira de Química/SBQ. Recuperado de https://www.sbq.org.br/46ra/anexos/anais-46rasbq.pdf -
NLM
Waitman K de B, Tavares MT, Almeida LC de, Carlos JAEG, Kronenberger T, Toledo MFZJ, Lotufo LVC, Machado Neto JA, Parise Filho R. Design and synthesis of new potential PI3K and HDAC6 hybrid inhibitors for cancer treatment [Internet]. Anais. 2023 ;[citado 2024 abr. 30 ] Available from: https://www.sbq.org.br/46ra/anexos/anais-46rasbq.pdf -
Vancouver
Waitman K de B, Tavares MT, Almeida LC de, Carlos JAEG, Kronenberger T, Toledo MFZJ, Lotufo LVC, Machado Neto JA, Parise Filho R. Design and synthesis of new potential PI3K and HDAC6 hybrid inhibitors for cancer treatment [Internet]. Anais. 2023 ;[citado 2024 abr. 30 ] Available from: https://www.sbq.org.br/46ra/anexos/anais-46rasbq.pdf - Purine-derived phenylhydroxamate compounds reduce cell viability and modulate HDAC activity in hematological neoplasm models
- Design of new potential PI3K and HDAC6 hybrid inhibitors for cancer treatment
- HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents
- Purine-derived Phenylhydroxamate compounds induces cell death in hematological neoplasm models
- AD80, a multikinase inhibitor, as a potential drug candidate for colorectal cancer therapy
- DNA damaging agents and DNA repair: from carcinogenesis to cancer therapy
- A novel HDAC inhibitor potentiates Venetoclax-induced apoptosis in acute myeloid leukemia cells
- Synthesis and biological evaluation of hybrid inhibitors for the treatment of hematologic malignancies
- Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors
- ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
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