Abnormal inhibin A and inhibin B secretion in obese women with and without insulin resistance (2005)
- Authors:
- Autor USP: ALDRIGHI, JOSE MENDES - FSP
- Unidade: FSP
- DOI: 10.1080/09513590500128716
- Subjects: OBESIDADE; OVULAÇÃO; HORMÔNIOS PEPTÍDICOS; CORPO LÚTEO (FORMAÇÃO); HORMÔNIOS DO PÂNCREAS ENDÓCRINO (RESISTÊNCIA)
- Language: Inglês
- Abstract: Aim: The present study aimed to establish inhibin A and B serum levels during the menstrual cycle of obese women, and its usefulness as an index of luteal-phase follicular development. Materials and methods.Twenty-one obese patients (mean body mass index: 34.90±03.7?kg/m2; range: 30.0-45.0?kg/m2) were submitted to basal hormonal measurements and an oral glucose tolerance test after challenge with 750g glucose. Progesterone and inhibin A and B levels were determined 5-7 days after the menstrual cycle and 7 days prior to expected menses. Results:As expected, an increase in inhibin A and a decrease in inhibin B were observed when first-phase samples were compared with samples obtained after 15-20 days. On the other hand, the percentage variation of both inhibin A and B was at least four times smaller than the values for normal women described previously by other authors employing the same enzyme-linked immunosorbent assays. A small number of obese women presented ovulatory cycles characterized by progesterone concentration higher than 5.80ng/ml. The percentage elevation (0>0190 percent) of inhibin A in the second samples was in agreement with the progesterone levels, but it seemed to be more sensitive for the detection of follicle luteinization.Conclusion: We conclude that obese women present less percentage variation of both inhibin A and B during the menstrual cycle, associated with a low frequency of ovulatory cycles. In obese women, the percentageincrease of inhibin A can represent an additional marker to recognize follicle luteinization
- Imprenta:
- Source:
- Título do periódico: Gynecological endocrinology
- ISSN: 0951-3590
- Volume/Número/Paginação/Ano: v. 21, n. 1, p. 7-11, 2005
- Este periódico é de assinatura
- Este artigo NÃO é de acesso aberto
- Cor do Acesso Aberto: closed
-
ABNT
AUGE, Antonio Pedro Flores et al. Abnormal inhibin A and inhibin B secretion in obese women with and without insulin resistance. Gynecological endocrinology, v. 21, n. 1, p. 7-11, 2005Tradução . . Disponível em: https://doi.org/10.1080/09513590500128716. Acesso em: 29 mar. 2024. -
APA
Auge, A. P. F., Longui, C. A., Prado, R. A. de A., Neves, M. R., Hirota, A., Busso, N. E., et al. (2005). Abnormal inhibin A and inhibin B secretion in obese women with and without insulin resistance. Gynecological endocrinology, 21( 1), 7-11. doi:10.1080/09513590500128716 -
NLM
Auge APF, Longui CA, Prado RA de A, Neves MR, Hirota A, Busso NE, Monte O, Aldrighi JM. Abnormal inhibin A and inhibin B secretion in obese women with and without insulin resistance [Internet]. Gynecological endocrinology. 2005 ; 21( 1): 7-11.[citado 2024 mar. 29 ] Available from: https://doi.org/10.1080/09513590500128716 -
Vancouver
Auge APF, Longui CA, Prado RA de A, Neves MR, Hirota A, Busso NE, Monte O, Aldrighi JM. Abnormal inhibin A and inhibin B secretion in obese women with and without insulin resistance [Internet]. Gynecological endocrinology. 2005 ; 21( 1): 7-11.[citado 2024 mar. 29 ] Available from: https://doi.org/10.1080/09513590500128716 - Efeitos do raloxifeno comparado a terapêutica de reposição hormonal contendo estradiol associado a progestógeno sobre a complacência vascular, em mulheres idosas com hipertensão arterial sistêmica
- Comparison between raloxifene and hormone replacement therapy on ambulatory blood pressure and arterial stiffness
- Efeitos da terapêutica de reposição hormonal transdérmica combinada e do raloxifeno sobre a proteína C reativa e anticorpos anti-LDL oxidada
- Efeito da terapia de reposição hormonal na complacência vascular em mulheres na pós-menopausa
- Effects of hormone replacement therapy or raloxifene on ambulatory blood pressures and arterial stoffness in treated hypertensive postmenopausal women
- Papel da terapia da reposição hormonal I: lípide, glicose, distribuição da gordura corpórea e endotélio
- Prevenção primária da doença cardiovascular na mulher
- Cardiopatia na mulher
- Qualidade do sono em mulheres paulistanas no climatério
- Epidemiologia e fatores de risco da doença cardiovascular após a menopausa
Informações sobre o DOI: 10.1080/09513590500128716 (Fonte: oaDOI API)
How to cite
A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas