Ver registro no DEDALUS
Exportar registro bibliográfico



Immunogenetics of leishmanial and mycobacterial infection: the Belem family study (1997)

  • Authors:
  • USP affiliated authors: SHAW, JEFFREY JON - ICB
  • USP Schools: ICB
  • DOI: 10.1098/rstb.1997.0118
  • Language: Inglês
  • Imprenta:
  • Source:
  • Acesso online ao documento

    DOI or search this record in
    Informações sobre o DOI: 10.1098/rstb.1997.0118 (Fonte: oaDOI API)
    • Este periódico é de assinatura
    • Este artigo é de acesso aberto
    • URL de acesso aberto
    • Cor do Acesso Aberto: green

    Exemplares físicos disponíveis nas Bibliotecas da USP
    BibliotecaCód. de barrasNúm. de chamada
    ICB12100016691PC-ICB BMP SEP 1997
    How to cite
    A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas

    • ABNT

      BLACKWELL, J M; BLACK, G G; PEACOCK, C S; et al. Immunogenetics of leishmanial and mycobacterial infection: the Belem family study. Philosophical Transactions of the Royal Society of London B - Biological Sciences, London, v. 352, p. 1331-1345, 1997. DOI: 10.1098/rstb.1997.0118.
    • APA

      Blackwell, J. M., Black, G. G., Peacock, C. S., Miller, E. N., Sibthorpe, D., Gnananandha, D., et al. (1997). Immunogenetics of leishmanial and mycobacterial infection: the Belem family study. Philosophical Transactions of the Royal Society of London B - Biological Sciences, 352, 1331-1345. doi:10.1098/rstb.1997.0118
    • NLM

      Blackwell JM, Black GG, Peacock CS, Miller EN, Sibthorpe D, Gnananandha D, Shaw JJ, Silveira F, Lins-Lainson Z, Ramos F, Collins A, Shaw MA. Immunogenetics of leishmanial and mycobacterial infection: the Belem family study. Philosophical Transactions of the Royal Society of London B - Biological Sciences. 1997 ; 352 1331-1345.
    • Vancouver

      Blackwell JM, Black GG, Peacock CS, Miller EN, Sibthorpe D, Gnananandha D, Shaw JJ, Silveira F, Lins-Lainson Z, Ramos F, Collins A, Shaw MA. Immunogenetics of leishmanial and mycobacterial infection: the Belem family study. Philosophical Transactions of the Royal Society of London B - Biological Sciences. 1997 ; 352 1331-1345.

    Referências citadas na obra
    Autor: Abel L.
    Título: Linkage of leprosy to the human NRAMP1 gene in Vietnamese families
    Título do periódico: Braz. J. Genet.
    Volume: 19
    Primeira página: 113
    Ano: 1996
    DOI: 10.1093/infdis/163.4.853
    DOI: 10.1084/jem.179.5.1683
    Barton C. H. Whitehead S. H. & Blackwell J. M. 1995 Nramp transfection transfers Ity/Lsh/Bcg-related pleiotropic e¡ects on macrophage activation: in£uence on oxidative burst and nitric oxide pathways. Molec. Med. 1 267^279.
    Black G. F. Shaw M.-A. Peacock C. S. Miller E. N. Shaw J. J. Silveira F. Lins-Lainson Z. Ramos F. & Blackwell J. M. 1998 Allelic association between IL-4 polymorphisms and the immune response to mycobacterial antigens. (In preparation.)
    Blackwell J. M. 1983 Leishmania donovani infection in heterozygous and recombinant H-2 haplotype mice. Immunogenetics 18 101^109.
    Blackwell J. M. 1989 The macrophage resistance gene Lsh/ Ity/Bcg (Convenor 27th Forum in Immunology). Res. Immunol. 140 767^828.
    Blackwell J. M. 1996 Structure and function of the naturalresistance-associated macrophage protein (Nramp1) a candidate protein for infectious and autoimmune disease susceptibility. Molec. Med.Today 2 205^211.
    DOI: 10.1002/eji.1830171125
    DOI: 10.1038/283072a0
    Blackwell J. M. Hale C. Roberts M. B. Ulczak O. M. Liew F. Y. & Howard J. G. 1985 An H-11-linked gene has a parallel e¡ect on Leishmania major and L. donovani infections in mice. Immunogenetics 21 385^395.
    DOI: 10.1016/0165-2478(91)90032-6
    Blackwell J. M. Barton C. H. White J. K. Searle S. Baker A.-M. Williams H. & Shaw M.-A. 1995 Genomic organization and sequence of the human NRAMP gene: identi¢cation and mapping of a promoter region polymorphism. Molec. Med. 1 194^205.
    DOI: 10.1016/0165-2478(94)00161-8
    Autor: Bradley D. J.
    Título: Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse
    Título do periódico: Clin. Exp. Immunol.
    Volume: 37
    Primeira página: 14
    Ano: 1979
    Buu N. T. Cellier M. Gros P. & Schurr E. 1995 Identi¢cation of a highly polymorphic length variant in the 3'UTR of NRAMP1. Immunogenetics 42 428^429.
    DOI: 10.1084/jem.182.5.1259
    Caceres-Dittmar G. Tapia F. J. Sanchez M. A. Yamamura M. Uyemura K. Modlin R. L. Bloom B. R. & Convit J. 1993 Determination of the cytokine pro¢le in American cutaneous leishmaniasis using the polymerase chain reaction. Clin. Exp. Immunol. 91 500^505.
    Cellier M. Belouchi A. & Gros P. 1996 Resistance to intracellular infections: comparative genomic analysis of Nramp. Trends Genet. 12 201^204.
    Clerget Darpoux F. Bonaiti Pellie C. & Hochez J. 1986 E¡ects of misspecifying genetic parameters in lod score analysis. Biometrics 42 393^399.
    Collins A. Frezal J. Teague J. & Morton N. E. 1996a A metric map of humans: 23 5000 loci in 850 bands. Proc. Natn. Acad. Sci. USA 93 14771^14775. Available through the Internet (
    Collins A. MacLean C. J. & Morton N. E. 1996b Trials of the beta model for complex inheritance. Proc. Natn. Acad. Sci. USA 93 9177^9181.
    DOI: 10.1038/ng0195-80
    Davies J. L. Kawaguchi Y. Bennett S. T. Copeman J. B. Cordell H. J. Pritchard L. E. Reed P. W. Gough S. C. Jenkins S. C. Palmer S. M. Balfour K. M. Rowe B. R. Farrall M. Barnett A. H. Bain S. C. & Todd J. A. 1994 A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371 130^136.
    Autor: Devergne O.
    Título: Production of the RANTES chemokine in delayed-type hypersensitivity reactions: involvement of macrophages and endothelial cells
    Título do periódico: J. Exp. Med.
    Volume: 179
    Ano: 1994
    DOI: 10.1164/ajrccm.153.4.8616554
    Govoni G. Vidal S. Gauthier S. Skamene E. Malo D. & Gros P. 1996 The Bcg/Ity/Lsh locus: genetic transfer of resistance to infections in C57BL/6J mice transgenic for the Nramp1Gly169 allele. Infect. Immun 64 2923^2929.
    Guler M. L. Gorham J. D. Hseih C. S. Mackey A. J. Steen R. G. Dietrich W. F. & Murphy K. M. 1996 Genetic susceptibility to Leishmania: IL-12 responsiveness in Th1 cell development. Science 271 984^987.
    DOI: 10.1093/nar/16.2.781
    Autor: Holmans P.
    Título: E¤ciency of typing unaffected relatives in an a¡ected sib-pair linkage study with single locus and multiple tightly-linked markers
    Título do periódico: Am. J. Hum. Genet.
    Volume: 57
    Ano: 1995
    Howard J. G. Hale C. & Chan-Liew W. L. 1980 Immunological regulation of experimental cutaneous leishmaniasis. I. Immunogenetic aspects of susceptibility to Leishmania tropica in mice. Parasite Immunol. 2 303^314.
    Autor: Jiang Y.
    Título: Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes
    Título do periódico: J. Immunol.
    Volume: 148
    Ano: 1992
    Kaye P. M. & Blackwell J. M. 1989 Lsh antigen presentation and the development of CMI. Res. Immunol. 140 810^815.
    Kramnik I. Radzioch D. & Skamene E. 1994 T-helper 1- like subset selection in Mycobacterium bovis bacillus Calmette-Gue rin-infected resistant and susceptible mice. Immunology 81 618^625.
    Lalouel J. M. & Morton N. E. 1981 Complex segregation analysis with pointers. Hum. Hered. 31 312^321.
    Lander E. & Kruglyak L. 1995 Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genet. 11 241^247.
    Lang T. Prina E. Sibthorpe D. & Blackwell J. M. 1997 Nramp1 transfection transfers Ity/Lsh/Bcg-related pleiotropic e¡ects on macrophage activation: in£uence on antigen processing and presentation. Infect. Immun. 65 380^386.
    Lewis L.-A. Victor T. Hoal-van Helden E. Blackwell J. M. Tullett S. Ehlers M. Beyers N. Donald P. & Helden P. van. 1996 Identi¢cation of a C to T mutation at position -236bp in the human NRAMP1 promoter. Immunogenetics 44 309^311.
    Lio P. & Morton N. E. 1997 Comparison of parametric and nonparametric methods to map oligogenes by linkage. Proc. Natn. Acad. Sci. USA (In the press.)
    Autor: Liu J.
    Título: Identi¢cation of polymorphisms and sequence variants in human homologue of the mouse natural resistance-associated macrophage protein gene
    Título do periódico: Am. J. Hum. Genet.
    Volume: 56
    Ano: 1995
    Marquet S. Laurent A. Hillaire D. Dessein H. Kalil J. Feingold J. Weissenbach J. & Dessein A. J. 1996 Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33. Nature Genet. 14 181^184.
    DOI: 10.1084/jem.183.3.1045
    DOI: 10.1084/jem.173.1.209
    DOI: 10.1111/j.1744-313X.1993.tb00153.x
    Autor: Morton N. E.
    Título: Sequential tests for the detection of
    Título do periódico: Linkage. Am. J. Hum. Genet.
    Volume: 7
    Ano: 1955
    Morton N. E. 1996 Logarithm of odds (lods) for linkage in complex inheritance. Proc. Natn. Acad. Sci. USA 93 3471^3476.
    Morton N. E. Shields D. C. & Collins A. 1991 Genetic epidemiology of complex phenotypes. Ann. Hum. Genet. 55 301^314.
    Mouse Genome 1996 Continuation of Mouse Newsletter 94 (1).
    Mouse Genome 1997 Continuation of Mouse Newsletter 95 (1).
    DOI: 10.1093/nar/19.13.3763
    Autor: Nedospasov S. A.
    Título: DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the Iymphotoxin (TNF-Þ) gene
    Título do periódico: J. Immunol.
    Volume: 147
    Ano: 1991
    Orme I. 1985 Only two out of ¢fteen BCG strains follow the Bcg pattern. Prog. Leuk. Biol. 3 285^289.
    Ott J. 1991 Analysis of human genetic linkage. Baltimore MD: The Johns Hopkins University Press.
    Papiha S. S. Wentzel J. Behjati F. & Agarwal S. S. 1985 Human leukocyte antigens and circulating immunoglobulin levels in Indian patients with pulmonary tuberculosis.Tubercle 66 25^33.
    Peacock C. S. Shaw M.-A. Miller N. Shaw J. J. Silveira F. Sanjeevi C. B. March R. Campbell D. Collins A. & Blackwell J. M. 1998 Analysis of the role of MHC genes in genetic susceptibility to visceral leishmaniasis. (In preparation.)
    Autor: Pirmez C.
    Título: Immunologic responsiveness in American cutaneous leishmaniasis lesions
    Título do periódico: J. Immunol.
    Volume: 145
    Ano: 1990
    DOI: 10.1172/JCI116341
    Radzioch D. Kramnik I. & Skamene E. 1995 Molecular mechanisms of natural resistance to mycobacterial infections. Circ. Shock 44 115^120.
    Autor: Risch N.
    Título: Linkage strategies for genetically complex traits. II. The power of a¡ected relative pairs
    Título do periódico: Am. J. Hum. Genet.
    Volume: 46
    Ano: 1990
    Autor: Risch N.
    Título: Linkage and mode of inheritance in complex traits. In Multipoint mapping and linkage based upon a¡ected pedigree members
    Título do periódico: Genetic Analysis Workshop
    Volume: 6
    Primeira página: 188
    Ano: 1989
    Autor: Roach T. I. A.
    Título: Macrophage activation: lipoarabinomannan (LAM) from avirulent and virulent strains of Mycobacterium tuberculosis di¡erentially induces the early genes c-fos, KC, JE and TNF-alpha
    Título do periódico: J. Immunol.
    Volume: 150
    Ano: 1993
    Roach T. I. A. Barton C. H. Chatterjee D. Liew F. Y. & Blackwell J. M. 1995 Opposing e¡ects of interferongamma on iNOS and IL10 expression in LPS and mycobacterial LAM stimulated macrophages. Immunology 85 106^113.
    Roach T. I. A. Chatterjee D. & Blackwell J. M. 1994 Induction of early response genes KC and JE by mycobacterial lipoarabinomannans: regulation of KC expression in murine macrophages by Lsh/Ity/Bcg (candidate Nramp). Infect. Immun. 62 1176^1184.
    Roberts M. Alexander J. & Blackwell J. M. 1989 In£uence of Lsh H-2 and an H-11-linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice. Infect. Immun. 57 875^881.
    DOI: 10.1111/j.1744-313X.1990.tb00862.x
    DOI: 10.1111/j.1744-313X.1993.tb00154.x
    Saltman D. L. Dolganov G. M. Warrington J. A. Wasmuth J. J. & Lovett M. 1993 A physical map of 15 loci on human chromosome 5q23-q33 by two-color £uorescence in situ hybridization. Genomics 16 726^732.
    Schall T. J. Bacon K. Toy K. J. & Goeddel D. V. 1990 Selective attraction of monocytes and T Iymphocytes of the memory phenotype by cytokine RANTES. Nature 347 669^671.
    Searle S. Bright N. Atkinson P. Barton C. H. & Blackwell J. M. 1997 Confocal and EM gold localization of Nramp1 to the late endosomal and Iysosomal compartments of murine macrophages. Cell Biology. (Submitted.)
    Sham P. C. & Curtis D. 1995 An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann. Hum. Genet. 59 323^336.
    DOI: 10.1136/jmg.33.8.672
    Shaw M.-A. Collins A. Peacock C. S. Miller E. N. Black G. F. Sibthorpe D. Lins-Lainson Z. Shaw J. J. Ramos F. Silveira F. & Blackwell J. M. 1997 Evidence that genetic susceptibility to Mycobacterium tuberculosis in a Brazilian population is under two-locus oligogenic control: linkage study of the candidate genes NRAMP1 and TNFA. Tubercle Lung Dis. (In the press.)
    Shaw M.-A. Blackwell J. M. & Collins A. 1998 Susceptibility to leprosy is linked to TNF and HLA-DRb in multi-case families. (In preparation.)
    Sieling P. A. & Modlin R. L. 1994 Cytokine patterns at the site of mycobacterial infection. Immunobiology 191 378^387.
    Skamene E. 1994 The Bcg gene story. Immunobiology 191 451^460.
    Surcel H.-M. Troye-Blomberg M. Paulie S. Andersson G. Moreno C. & Pasvol G. 1994 Th1/Th2 pro¢les in tuberculosis based on the proliferation and cytokine response of blood Iymphocytes to mycobacterial antigens. Immunology 81 171^176.
    Terwilliger J. D. & Ott J. 1992 A haplotype-based `haplotype relative risk' approach to detecting allelic associations. Hum. Hered. 42 337^346.
    DOI: 10.1084/jem.176.1.59
    Vidal S. M. Malo D. Vogan K. Skamene E. & Gros P. 1993 Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell 73 469^485.
    DOI: 10.1084/jem.182.3.655
    Vieland V. J. Greenberg D. A. Hodge S. E. & Ott J. 1992 Linkage analysis of two-locus diseases under single-locus and two-locus analysis models. Cytogenet. Cell. Genet. 59 145^146.
    Autor: Weber J. L.
    Título: Dinucleotide repeat polymorphisms at the D17S250 and D17S261 loci
    Título do periódico: Nucleic Acids Res.
    Volume: 18
    Primeira página: 4640
    Ano: 1990
    Weeks D. E. Lehner T. Squires Wheeler E. Kaufmann C. & Ott J. 1990 Measuring the in£ation of the lod score due to its maximization over model parameter values in human linkage analysis. Genet. Epidemiol. 7 237^243.
    White J. K. Shaw M.-A. Barton C. H. Cerretti D. P. Williams H. Mock B. A. Carter N. P. Peacock C. S. & Blackwell J. M. 1994 Genetic and physical mapping of 2q35 in the region of NRAMP and IL8R genes: identi¢cation of a polymorphic repeat in exon 2 of NRAMP. Genomics 24 295^302.
    DOI: 10.1093/hmg/1.5.353
    Autor: Xu J.
    Título: Evidence for two unlinked loci regulating total serum IgE levels
    Título do periódico: Am. J. Hum. Genet.
    Volume: 57
    Ano: 1995
    Yamamura M. Uyemura K. Deans R. J. Weinberg K. Rea T. H. Bloom B. R. & Modlin R. L. 1991 De¢ning protective responses to pathogens: cytokine pro¢les in leprosy lesions. Science 254 277^279.
    Autor: Yamamura M.
    Título: Cytokine patterns of immunologically mediated tissue damage
    Título do periódico: J. Immunol.
    Volume: 149
    Ano: 1992
    DOI: 10.1084/jem.171.6.2177