Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages (2003)
- Authors:
- USP affiliated authors: LARA, VANESSA SOARES - FOB ; CUNHA, FERNANDO DE QUEIROZ - FMRP
- Unidades: FOB; FMRP
- Subjects: ÓXIDO NÍTRICO; CÉLULAS; RAIZ DENTÁRIA
- Language: Inglês
- Abstract: The activation of inflammatory cells and consequent release of mediators play an important role in the resorption of mineralized tissues. In the present study, we examined the ability of dentin extracts to induce inflammatory cell recruitment and activation. We showed here that dentin extracts triggered an intense cell migration and progressive cell maturation, in a time and dose dependent manner. Expression of interleukin-1 'beta' (IL-1'beta'), tumor necrosis factor-'alfa' (TNF-'alfa'), nitric oxide (NO), and hydrogen peroxide ('H IND.2''O IND.2') was also up-regulated by dentin extracts. These results show that inflammatory events can be elicited in response to dentin, which may suggest a possible involvement of dentin molecules in the inflammatory events, coupled with their release at the root resorption sites
- Imprenta:
- Source:
- Título do periódico: Journal of dental research
- ISSN: 0022-0345
- Volume/Número/Paginação/Ano: v. 82, n. 6, p. 460-465, 2003
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ABNT
LARA, Vanessa Soares et al. Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research, v. 82, n. 6, p. 460-465, 2003Tradução . . Acesso em: 23 abr. 2024. -
APA
Lara, V. S., Figueiredo, F., Silva, T. A. da, & Cunha, F. de Q. (2003). Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research, 82( 6), 460-465. -
NLM
Lara VS, Figueiredo F, Silva TA da, Cunha F de Q. Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research. 2003 ; 82( 6): 460-465.[citado 2024 abr. 23 ] -
Vancouver
Lara VS, Figueiredo F, Silva TA da, Cunha F de Q. Dentin-induced in vivo inflammatory response and in vitro activation of murine macrophages. Journal of dental research. 2003 ; 82( 6): 460-465.[citado 2024 abr. 23 ] - Mast cells phagocyte Candida albicans and produce nitric oxide by mechanisms involving TLR2 and Dectin-1
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- Cytokine and chemokine response of bone cells after dentin challenge in vitro
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- Differential expression of chemokines and chemokine receptors in inflammatory periapical diseases
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- Avaliação da expressão da enzima óxido nítrico-sintase induzível(INOS) por células CD68 positivas em doença periodontal humana
- Estudo comparativo da presença de mastócitos em gengivites associadas à placa bacteriana e periodontites crônicas localizadas
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