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Relative bioavailability of calcium-rich dietary sources in the elderly1-4 (2002)

  • Authors:
  • USP affiliated authors: MARTINI, LIGIA ARAUJO - FSP
  • USP Schools: FSP
  • DOI: 10.1093/ajcn/76.6.1345
  • Subjects: BIODISPONIBILIDADE; CÁLCIO (APLICAÇÕES TERAPÊUTICAS); CÁLCIO; SUPLEMENTAÇÃO ALIMENTAR
  • Language: Inglês
  • Abstract: Background: The recent increase in the dietary calcium recommendation from 800 to 1200 mg/d for persons aged > 51 y has made it important to identify alternative high-calcium dietary sources that the elderly can use in meeting their calcium requirement. Objective: We determined the bioavailability of calcium from 3 different sources: orange juice fortified with calcium-citrate malate, skim milk, and a calcium carbonate supplement. Design: Twelve subjects [9 women and 3 men with a mean (± SEM) age of 70 ± 3 and 76 ± 6 y, respectively] consumed low-calcium (300 mg/d) and high-calcium (1300 mg/d) diets for three 1-wk periods each during a 6-wk crossover study. The acute biochemical response to calcium from each of the 3 sources was assessed during a 4-h period after the initial breakfast meal of the high-calcium diet. Results: Postprandial suppression of serum parathyroid hormone did not differ significantly between the test meals containing calcium-fortified orange juice, the calcium carbonate supplement, and milk. This finding suggests that the calcium bioavailability from the 3 sources was equivalent. During the 1-wk high-calcium diet periods, fasting serum calcium increased by 3 percent (P < 0.0001), serum 1,25-dihydroxyvitamin D decreased by 20 percent (P < 0.0001), and a biomarker of bone resorption (serum N-telopeptide collagen cross-links) decreased by 14 percent (P < 0.02) compared with the low-calcium diet period. However, no differences amongthe supplemental calcium sources were found in these calcium-responsive measures or fasting serum parathyroid hormone concentration. Conclusions: In elderly subjects, the calcium bioavailability of the 3 high-calcium dietary sources tested was equivalent, during both the acute postprandial and longer-term periods
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    Informações sobre o DOI: 10.1093/ajcn/76.6.1345 (Fonte: oaDOI API)
    • Este periódico é de assinatura
    • Este artigo é de acesso aberto
    • URL de acesso aberto
    • Cor do Acesso Aberto: bronze
    Informações sobre o Citescore
  • Título: American Journal of Clinical Nutrition

    ISSN: 0002-9165

    Citescore - 2017: 5.62

    SJR - 2017: 3.438

    SNIP - 2017: 2.191


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    • ABNT

      MARTINI, Lígia Araújo; WOOD, Richard J. Relative bioavailability of calcium-rich dietary sources in the elderly1-4. American Journal of Clinical Nutrition, Bethesda, v. 76, n. 6, p. 1345-1350, 2002. DOI: 10.1093/ajcn/76.6.1345.
    • APA

      Martini, L. A., & Wood, R. J. (2002). Relative bioavailability of calcium-rich dietary sources in the elderly1-4. American Journal of Clinical Nutrition, 76( 6), 1345-1350. doi:10.1093/ajcn/76.6.1345
    • NLM

      Martini LA, Wood RJ. Relative bioavailability of calcium-rich dietary sources in the elderly1-4. American Journal of Clinical Nutrition. 2002 ; 76( 6): 1345-1350.
    • Vancouver

      Martini LA, Wood RJ. Relative bioavailability of calcium-rich dietary sources in the elderly1-4. American Journal of Clinical Nutrition. 2002 ; 76( 6): 1345-1350.