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New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders (2007)

  • Authors:
  • USP affiliated authors: BRITTO, LUIZ ROBERTO GIORGETTI DE - ICB ; ULRICH, ALEXANDER HENNING - IQ
  • USP Schools: ICB; IQ
  • DOI: 10.1007/s11302-007-9074-y
  • Subjects: FISIOLOGIA
  • Language: Inglês
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    Informações sobre o DOI: 10.1007/s11302-007-9074-y (Fonte: oaDOI API)
    • Este periódico é de assinatura
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  • Título: Purinergic Signalling

    ISSN: 1573-9538

    Citescore - 2017: 3.29

    SJR - 2017: 1.104

    SNIP - 2017: 0.822


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    • ABNT

      MAJUMDER, Paromita; TRUJILLO, Cleber A.; LOPES, Camila G.; et al. New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic Signalling, Dordrecht, v. 3, n. 4, p. 317-331, 2007. DOI: 10.1007/s11302-007-9074-y.
    • APA

      Majumder, P., Trujillo, C. A., Lopes, C. G., Resende, R. R., Gomes, K. N., Yuahasi, K. K., et al. (2007). New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic Signalling, 3( 4), 317-331. doi:10.1007/s11302-007-9074-y
    • NLM

      Majumder P, Trujillo CA, Lopes CG, Resende RR, Gomes KN, Yuahasi KK, Britto LRG de, Ulrich AH. New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic Signalling. 2007 ; 3( 4): 317-331.
    • Vancouver

      Majumder P, Trujillo CA, Lopes CG, Resende RR, Gomes KN, Yuahasi KK, Britto LRG de, Ulrich AH. New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic Signalling. 2007 ; 3( 4): 317-331.

    Referências citadas na obra
    Evans RJ, Derkach V, Surprenant A (1992) ATP mediates fast synaptic transmission in mammalian neurons. Nature 357:503–505
    Silinsky EM, Gerzanich V, Vanner SM (1992) ATP mediates excitatory synaptic transmission in mammalian neurones. Br J Pharmacol 106:762–763
    Burnstock G (1978) A basis for distinguishing two types of purinergic receptor. In: Straub RW, Bolis L (eds) Cell membrane receptors for drugs and hormones: a multidisciplinary approach. Raven, New York, pp 107–118
    Burnstock G, Kennedy C (1985) Is there a basis for distinguishing two types of P2 purinoceptor? Gen Pharmacol 16:433–440
    Brandle U, Zenner H-P, Ruppersberg JP (1999) Gene expression of P2X receptors in the developing inner ear of the rat. Neurosci Lett 273:105–108
    Adrian K, Bernhard MK, Breitinger H-G et al (2000) Expression of purinergic receptors (ionotropic P2X1-7 and metabotrophic P2Y1-11) during myeloid differentiation of HL60 cells. Biochim Biophys Acta 1492:127–138
    Orriss, IR, Knight GE, Ranasinghe S et al (2006) Osteoblast responses to nucleotides increase during differentiation. Bone 39:300–309
    Berchtold S, Ogilvie ALL, Bogdan C et al (1999) Human monocyte derived dendritic cells express functional P2X and P2Y receptors as well as ecto-nucleotidases. FEBS Lett 458:424–428
    Ryten M, Dunn PM, Neary JT et al (2002) ATP regulates the differentiation of mammalian skeletal muscle by activation of a P2X5 receptor on satellite cells. J Cell Biol 158:345–355
    Wang L, Jacobsen SE, Bengtsson A et al (2004) P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells. BMC Immunol 5:16
    Huang N, Wang DJ, Heppel LA (1989) Extracellular ATP is a mitogen for 3T3, 3T6, and A431 cells and acts synergistically with other growth factors. Proc Natl Acad Sci U S A 86:7904–7908
    Neary JT, Whittemore SR, Zhu Q et al (1994). Synergistic activation of DNA synthesis in astrocytes by fibroblast growth factor and extracellular ATP. J Neurochem 63:490–494
    Lemoli RM, Ferrari D, Fogli M et al (2004) Extracellular nucleotides are potent stimulators of human hematopoietic stem cells in vitro and in vivo. Blood 104:1662–1670
    Neary JT, Zhu Q (1994) Signaling by ATP receptors in astrocytes. Neuroreport 5:1617–1620
    Lenz G, Gottfried C, Luo ZJ et al (2000) P2Y purinoceptor subtypes recruit different Mek activators in astrocytes. Br J Pharmacol 129:927–936
    Salter M, Hicks JL (1995) ATP causes release of intracellular Ca2+ via the phospholipase C beta/IP3 pathway in astrocytes from the dorsal spinal cord. J Neurosci 15:2961–2971
    Miranov SL (1994) Metabotropic ATP receptor in hippocampal and thalamic neurones: pharmacology and modulation of Ca2+ mobilizing mechanisms. Neuropharmacology 33:1–13
    Spitzer NC, Root CM, Borodinsky LN (2004) Orchestrating neuronal differentiation: patterns of Ca2+ spikes specify transmitter choice. Trends Neurosci 27:415–421
    Gu X, Spitzer NC (1997) Breaking the code: regulation of neuronal differentiation by spontaneous calcium transients. Dev Neurosci 19:33–41
    Zimmermann H (1996) Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system. Prog Neurobiol 49:589–618
    Götz M, Huttner WB (2005) The cell biology of neurogenesis. Nat Rev Mol Cell Biol 6:777–788
    Abbracchio MP, Burnstock G (1998) Purinergic signaling: pathophysiological roles. Jpn J Pharmacol 78:113–145
    Laasberg T (1990) Ca2+-mobilizing receptors of gastrulating chick embryo. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 97:9–12
    Katz LC, Shatz CJ (1996) Synaptic activity and the construction of cortical circuits. Science 274:1133–1138
    Weissman TA, Riquelme PA, Ivic L et al (2004) Calcium waves propagate through radial glial cells and modulate proliferation in the developing neocortex. Neuron 43:647–661
    Cicirata F, Meli C, Castorina C et al (1991) Neurotransmitter amino acid levels in rat thalamus and cerebral cortex after cerebellectomy. Int J Dev Neurosci 9:365–369
    Miranda-Contreras L, Mendoza-Briceno RV, Palacios-Pru EL (1998) Levels of monoamine and amino acid neurotransmitters in the developing male mouse hypothalamus and in histotypic hypothalamic cultures. Int J Dev Neurosci 16:403–412
    Miranda-Contreras L, Benitez-Diaz PR, Mendoza-Briceno RV et al (1999) Levels of amino acid neurotransmitters during mouse cerebellar neurogenesis and in histotypic cerebellar cultures. Dev Neurosci 21:147–158
    Miranda-Contreras L, Ramirez-Martens LM, Benitez-Diaz PR et al (2000) Levels of amino acid neurotransmitters during mouse olfactory bulb neurogenesis and in histotypic olfactory bulb cultures. Int J Dev Neurosci 18:83–91
    Flint AC, Liu X, Kriegstein AR (1998) Nonsynaptic glycine receptor activation during early neocortical development. Neuron 20:43–53
    Haydar TF, Wang F, Schwartz ML et al (2000) Differential modulation of proliferation in the neocortical ventricular and subventricular zones. J Neurosci 20:5764–5774
    Evans MJ, Kaufman M (1981) Establishment in culture of pluripotent cells from mouse embryos. Nature 292:154–156
    McWhir J, Schnieke AE, Ansell R et al (1996) Selective ablation of differentiated cells permits isolation of embryonic stem cell lines from murine embryos with a non-permissive genetic background. Nat Genet 14:223–226
    Heo SJ, Han HJ (2006) ATP stimulates mouse embryonic stem cell proliferation via protein kinase C, phosphatidylinositol 3-kinase/Akt, and mitogen-activated protein kinase signaling pathways. Stem Cells 24:2637–2648
    Anneren C, Cowan CA, Melton DA (2004) The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. J Biol Chem 279:31590–31598
    Martin GR (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78:7634–7638
    Ulrich H, Majumder P (2006) Neurotransmitter receptor expression and activity during neuronal differentiation of embryonal carcinoma and stem cells: from basic research towards clinical applications. Cell Prolif 39:281–300
    Resende RR, Majumder P, Gomes KN et al (2007) P19 embryonal carcinoma cells as in vitro model for studying purinergic receptor expression and modulation of N-methyl-d-aspartate-glutamate and acetylcholine receptors during neuronal differentiation. Neuroscience 146:1169–1181
    da Silva RL, Resende RR, Ulrich H (2007) Alternative splicing of P2X6 receptors in developing mouse brain and during in vitro neuronal differentiation. Exp Physiol 92:139–415
    Gage FH, Coates PW, Palmer TD et al (1995) Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci U S A 92:11879–11883
    Hogg RC, Chipperfield H, Whyte KA et al (2004) Functional maturation of isolated neural progenitor cells from the adult rat hippocampus. Eur J Neurosci 19:2410–2420
    Pluchino S, Zanotti L, Deleidi M et al (2005) Neural stem cells and their use as therapeutic tool in neurological disorders. Brain Res Rev 48:211–219
    Cameron HA, Tanapat P, Gould E (1998) Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway. Neuroscience 82:349–354
    Svendsen CN, ter Borg MG, Armstrong RJ et al (1998) A new method for the rapid and long term growth of human neural precursor cells. J Neurosci Methods 85:141–152
    Shukla V, Zimmermann H, Wang L et al (2005) Functional expression of the ecto-ATPase NTPDase2 and of nucleotide receptors by neuronal progenitor cells in the adult murine hippocampus. J Neurosci Res 80:600–610
    Braun N, Sevigny J, Mishra SK et al (2003) Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. Eur J Neurosci 17:1355–1364
    Mishra SK, Braun N, Shukla V et al (2006) Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation. Development 133:675–684
    Leon C, Hechler B, Freund M et al (1999) Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. J Clin Invest 104:1731–1737
    Lin JH, Takano T, Arcuino G et al (2007) Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. Dev Biol 302:356–366
    Ryu JK, Choi HB, Hatori K et al (2003) Adenosine triphosphate induces proliferation of human neural stem cells: role of calcium and p70 ribosomal protein S6 kinase. J Neurosci Res 72:352–362
    Tran PB, Ren D, Veldhouse TJ et al (2004) Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells. J Neurosci Res 76:20–34
    Safiulina VF, Kasyanov AM, Sokolova E et al (2005) ATP contributes to the generation of network-driven giant depolarizing potentials in the neonatal rat hippocampus. J Physiol 565:981–992
    Heine C, Heimrich B, Vogt J et al (2006) P2 receptor-stimulation influences axonal outgrowth in the developing hippocampus in vitro. Neuroscience 138:303–311
    Burnstock G (1996) Development and perspectives of the purinoceptor concept. J Auton Pharmacol 16:295–302
    Torres IL, Battastini AM, Buffon A et al (2003) Ecto-nucleotidase activities in spinal cord of rats changes as function of age. Int J Dev Neurosci 21:425–429
    Cheung KK, Burnstock G (2002) Localization of P2X3 receptors and coexpression with P2X2 receptors during rat embryonic neurogenesis. J Comp Neurol 443:368–382
    Cheung KK, Ryten M, Burnstock G (2003) Abundant and dynamic expression of G protein-coupled P2Y receptors in mammalian development. Dev Dyn 228:254–266
    Cheung KK, Chan WY, Burnstock G (2005) Expression of P2X purinoceptors during rat brain development and their inhibitory role on motor axon outgrowth in neural tube explant cultures. Neuroscience 133:937–945
    Xiang Z, Burnstock G (2005) Expression of P2X receptors on rat microglial cells during early development. Glia 52:119–126
    Kidd EJ, Miller KJ, Sansum AJ et al (1998) Evidence for P2X3 receptors in the developing rat brain. Neuroscience 87:533–539
    Brosenitsch TA, Adachi T, Lipski J et al (2005) Developmental downregulation of P2X3 receptors in motoneurons of the compact formation of the nucleus ambiguous. Eur J Neurosci 22:809–824
    Narcisse L, Scemes E, Zhao Y et al (2005) The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes. Glia 49:245–258
    Sperlágh B, Köfalvi A, Deuchars D et al (2002) Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus. J Neurochem 81:1196–1211
    Feuvre RL, Brough D, Rothwell N (2002) Extracellular ATP and P2X7 receptors in neurodegeneration. Eur J Pharmacol 447:261–269
    Xiang Z, Burnstock G (2005) Changes in expression of P2X purinoreceptor in rat cerebellum during postnatal development. Dev Brain Res 156:147–157
    Lalo U, Voitenko N, Kostyuk P (1998) Iono- and metabotropically induced purinergic calcium signalling in rat neocortical neurons. Brain Res 799:285–291
    Ciccolini F, Collins TJ, Sudhoelter J et al (2003) Local and global spontaneous calcium events regulate neurite outgrowth and onset of GABAergic phenotype during neural precursor differentiation. J Neurosci 23:103–111
    Maric D, Maric I, Chang YH et al (2003) Prospective cell sorting of embryonic rat neural stem cells and neuronal and glial progenitors reveals selective effects of basic fibroblast growth factor and epidermal growth factor on self-renewal and differentiation. J Neurosci 23:240–251
    Scemes E, Duval N, Meda P (2003) Reduced expression of P2Y1 receptors in connexin43-null mice alters calcium signaling and migration of neural progenitor cells. J Neurosci 23:11444–11452
    Hyden H (1961) Satellite cells in the nervous system. Sci Am 205:62–70
    Vernadakis A (1996) Glia-neuron intercommunications and synaptic plasticity. Prog Neurobiol 49:185–214
    Imura T, Kornblum HI, Sofroniew MV (2003) The predominant neural stem cell isolated from postnatal and adult forebrain but not early embryonic forebrain expresses GFAP. J Neurosci 23:2824–2832
    Garcia AD, Doan NB, Imura T et al (2004) GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci 7:1233–1241
    Powell EM, Geller HM (1999) Dissection of astrocyte-mediated cues in neuronal guidance and process extension. Glia 26:73–83
    Merkle FT, Alvarez-Buylla A (2006) Neural stem cells in mammalian development. Curr Opin Cell Biol 18:704–709
    Song H, Stevens CF, Gage FH (2002) Astroglia induce neurogenesis from adult neural stem cells. Nature 417:39–44
    Svendsen CN (2002) The amazing astrocyte. Nature 417:29–32
    Montgomery DL (1994) Astrocytes: form, functions, and roles in disease. Vet Pathol 31:145–167
    Rose CR, Ransom BR (1997) Gap junctions equalize intracellular Na+ concentration in astrocytes. Glia 20:299–307
    Cotrina ML, Lin JH, Alves-Rodrigues A et al (1998) Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci U S A 95:15735–15740
    Cotrina ML, Lin JH, Nedergaard M (1998) Cytoskeletal assembly and ATP release regulate astrocytic calcium signaling. J Neurosci 18:8794–8804
    Ciccarelli R, Ballerini P, Sabatino G et al (2001) Involvement of astrocytes in purine-mediated reparative processes in the brain. Int J Dev Neurosci 19:395–414
    Fields RD, Stevens-Graham B (2002) New insights into neuron-glia communication. Science 298:556–562
    Hansson E, Ronnback L (2003) Glial neuronal signaling in the central nervous system. FASEB J 17:341–348
    Hagg T (2005) Molecular regulation of adult CNS neurogenesis: an integrated view. Trends Neurosci 28:589–595
    Araque A, Perea G (2004) Glial modulation of synaptic transmission in culture. Glia 47:241–248
    Lin SC, Bergles DE (2004) Synaptic signaling between neurons and glia. Glia 47:290–298
    Araque A, Carmignoto G, Haydon PG (2001) Dynamic signaling between astrocytes and neurons. Annu Rev Physiol 63:795–813
    Hertz L, Zielke HR (2004) Astrocytic control of glutamatergic activity: astrocytes as stars of the show. Trends Neurosci 27:735–743
    Cotrina ML, Lin JH, Lopez-Garcia JC et al (2000) ATP-mediated glia signaling. J Neurosci 20:2835–2844
    Fields RD, Burnstock G (2006) Purinergic signalling in neuron-glia interactions. Nat Rev Neurosci 7:423–436
    Chaudry IH (1982) Does ATP cross the cell plasma membrane. Yale J Biol Med 55:1–10
    Fields RD, Stevens B (2000) ATP: an extracellular signaling molecule between neurons and glia. Trends Neurosci 23:625–633
    Vizi ES, Burnstock G (1988) Origin of ATP release in the rat vas deferens: concomitant measurement of [3H]noradrenaline and [14C]ATP. Eur J Pharmacol 158:69–77
    Bodin P, Burnstock G (2001) Purinergic signalling: ATP release. Neurochem Res 26:959–969
    Edwards FA, Gibb AJ, Colquhoun D (1992) ATP receptor mediated synaptic currents in the central nervous system. Nature 359:144–146
    Mori M, Heuss C, Gahwiler BH et al (2001) Fast synaptic transmission mediated by P2X receptors in CA3 pyramidal cells of rat hippocampal slice cultures. J Physiol 535:115–123
    Reisin IL, Prat AG, Abraham EH et al (1994) The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel. J Biol Chem 269:20584–20591
    Schwiebert EM (1999) ABC transporter-facilitated ATP conductive transport. Am J Physiol 276:C1–C8
    Stout CE, Costantin JL, Naus CC et al (2002) Intercellular calcium signaling in astrocytes via ATP release through connexin hemichannels. J Biol Chem 277:10482–10488
    Suadicani SO, Brosnan CF, Scemes E (2006) P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J Neurosci 26:1378–1385
    Franke H, Krugel U, Illes P (2006) P2 receptors and neuronal injury. Pflugers Arch 452:622–644
    Zimmermann H (2000) Extracellular metabolism of ATP and other nucleotides. Naunyn Schmiedebergs Arch Pharmacol 362:299–309
    Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413–492
    Ribeiro JA, Sebastiao AM, de Mendonca A (2003) Participation of adenosine receptors in neuroprotection. Drug News Perspect 16:80–86
    Bennett MR, Buljan V, Farnell L et al (2006) Purinergic junctional transmission and propagation of calcium waves in spinal cord astrocyte networks. Biophys J 91:3560–3571
    Butt AM (2006) Neurotransmitter-mediated calcium signalling in oligodendrocyte physiology and pathology. Glia 54:666–675
    Walz W, Gimpl G, Ohlemeyer C et al (1994) Extracellular ATP-induced currents in astrocytes: involvement of a cation channel. J Neurosci Res 38:12–18
    Franke H, Illes P (2006) Involvement of P2 receptors in the growth and survival of neurons in the CNS. Pharmacol Ther 109:297–324
    Deitmer JW, Verkhratsky AJ, Lohr C (1998) Calcium signalling in glial cells. Cell Calcium 24:405–416
    Vesce S, Bezzi P, Volterra A (1999) The active role of astrocytes in synaptic transmission. Cell Mol Life Sci 56:991–1000
    Dani JW, Chernjavsky A, Smith SJ (1992) Neuronal activity triggers calcium waves in hippocampal astrocyte networks. Neuron 8:429–440
    Guthrie PB, Knappenberger J, Segal M et al (1999) ATP released from astrocytes mediates glial calcium waves. J Neurosci 19:520–528
    Zhang JM, Wang HK, Ye CQ et al (2003) ATP released by astrocytes mediates glutamatergic activity-dependent heterosynaptic suppression. Neuron 40:971–982
    Innocenti B, Parpura V, Haydon PG (2000) Imaging extracellular waves of glutamate during calcium signaling in cultured astrocytes. J Neurosci 20:1800–1808
    Fam SR, Gallagher CJ, Salter MW (2000) P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes. J Neurosci 20:2800–2808
    Domercq M, Brambilla L, Pilati E et al (2006) P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins. J Biol Chem 281:30684–30696
    Agrestia C, Meomartinib ME, Amadiob S et al (2005) ATP regulates oligodendrocyte progenitor migration, proliferation, and differentiation: involvement of metabotropic P2 receptors. Brain Res Rev 48:157–165
    Burnstock G (2006) Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev 58:58–86
    Gysbers JW, Rathbone MP (1992) Guanosine enhances NGF-stimulated neurite outgrowth in PC12 cells. Neuroreport 3(11):997–1000
    D’Ambrosi N, Cavaliere F, Merlo D et al (2000) Antagonists of P2 receptor prevent NGF-dependent neuritogenesis in PC12 cells. Neuropharmacology 39:1083–1094
    D’Ambrosi N, Murra B, Cavaliere F et al (2001) Interaction between ATP and nerve growth factor signalling in the survival and neuritic outgrowth from PC12 cells. Neuroscience 108:527–534
    Sanches G, de Alencar LS, Ventura AL (2002) ATP induces proliferation of retinal cells in culture via activation of PKC and extracellular signal-regulated kinase cascade. Int J Dev Neurosci 20:21–27
    Braumann T, Jastorff B, Richter-Landsberg C (1986) Fate of cyclic nucleotides in PC12 cell cultures: uptake, metabolism, and effects of metabolites on nerve growth factor-induced neurite outgrowth. J Neurochem 47:912–919
    Wang CM, Chang YY, Kuo JS et al (2002) Activation of P2X(7) receptors induced [(3)H]GABA release from the RBA-2 type-2 astrocyte cell line through a Cl(-)/HCO(3)(-))-dependent mechanism. Glia 37:8–18
    Kucher BM, Neary JT et al (2005) Bi-functional effects of ATP/P2 receptor activation on tumor necrosis factor-α release in lipopolysaccharide-stimulated astrocytes. J Neurochem 92:525–535
    Krügel U, Kittner H, Franke H et al (2001) Accelerated functional recovery after neuronal injury by P2 receptor blockade. Eur J Pharmacol 420:R3–R4
    Sebastião AM, de Mendonça A, Ribeiro JA et al (2001) Neuroprotection during hypoxic insults: role of adenosine. Drug Dev Res 52:291–295
    Kaya N, Tanaka S, Koike T et al (2002) ATP selectively suppresses the synthesis of the inflammatory protein microglial response factor (MRF)-1 through Ca2+ influx via P2X7 receptors in cultured microglia. Brain Res 952:86–97
    Gendron FP, Chalimoniuk M, Strosznajder J et al (2003) P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells. J Neurochem 87:344–352
    Ohtani Y, Minami M, Satoh M et al (2000) Expression of inducible nitric oxide synthase mRNA and production of nitric oxide are induced by adenosine triphosphate in cultured rat microglia. Neurosci Lett 293:72–74
    Ferrari D, Chiozzi P, Falzoni S et al (1997) Purinergic modulation of interleukin-1β release from microglial cells stimulated with bacterial endotoxin. J Exp Med 185:579–582
    Hide I, Tanaka M, Inoue A et al (2000) Extracellular ATP triggers tumor necrosis factor alpha release from rat microglia. J Neurochem 75:965–972
    Humphreys BD, Rice J, Kertesy SB et al (2000) Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor. J Biol Chem 275:26792–26798
    Shigemoto-Mogami Y, Koizumi S, Tsuda M et al (2001) Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5. J Neurochem 78:1339–1349
    Inoue K, Nakajima K, Morimoto T et al (1998) ATP stimulation of Ca2+-dependent plasminogen release from cultured microglia. Br J Pharmacol 123:1304–1310
    Khakh BS (2001) Molecular physiology of P2X receptors and ATP signalling at synapses. Nat Rev Neurosci 2:165–174
    Knutsen LJ, Murray TF et al (1997) Adenosine and ATP in epilepsy. In: Jacobson KA, Jarvis (eds) Purinergic approaches in experimental therapeutics. Wiley-Liss, Danvers, MA
    Kang TC, An SJ, Park SK et al (2003) P2X2 and P2X4 receptor expression is regulated by a GABA(A) receptor-mediated mechanism in the gerbil hippocampus. Mol Brain Res 116:168–175
    Kang TC, Park SK, Hwang IK et al (2004) GABA(B) receptor-mediated regulation of P2X7 receptor expression in the gerbil hippocampus. Mol Brain Res 121:12–18
    Stoeckel ME, Uhl-Bronner S, Hugel S et al (2003) Cerebrospinal fluid-contacting neurons in the rat spinal cord, a gamma-aminobutyric acidergic system expressing the P2X2 subunit of purinergic receptors, PSA-NCAM, and GAP-43 immunoreactivities: light and electron microscopic study. J Comp Neurol 457:159–174
    Labrakakis C, Tong CK, Weissman T et al (2003) Localization and function of ATP and GABAA receptors expressed by nociceptors and other postnatal sensory neurons in rat. J Physiol 549:131–142
    Chen CC, Akopian AN, Sivilotti L et al (1995) A P2X purinoceptor expressed by a subset of sensory neurons. Nature 377:428–431
    Lewis CJ, Neidhart S, Holy C et al (1995) Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurones. Nature 377:432–434
    Khakh BS, Humphrey PP, Surprenant A (1995) Electrophysiological properties of P2X-purinoceptors in rat superior cervical, nodose and guinea-pig coeliac neurones. J Physiol 484:385–395
    Cockayne DA, Hamilton SG, Zhu QM et al (2000) Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature 407:1011–1015
    Souslova V, Cesare P, Ding Y et al (2000) Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. Nature 407:1015–1017
    North RA (2003) The P2X3 subunit: a molecular target in pain therapeutics. Curr Opin Investig Drugs 4:833–840
    Jarvis MF, Burgard EC, McGaraughty S et al (2002) A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc Natl Acad Sci U S A 99:17179–17184
    Tsuda M, Shigemoto-Mogami Y, Koizumi S et al (2003) P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature 424:778–783
    Haughey NJ, Mattson MP (2003) Alzheimer’s amyloid beta-peptide enhances ATP/gap junction-mediated calcium-wave propagation in astrocytes. Neuromol Med 3:173–180
    Exley C, Korchazhkina OV (2001) Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP). J Inorg Biochem 84:215–224
    Rampe D, Wang L, Ringheim GE et al (2004) P2X7 receptor modulation of beta-amyloid- and LPS-induced cytokine secretion from human macrophages and microglia. J Neuroimmunol 147:56–61
    Parvathenani LK, Tertyshnikova S, Greco CR et al (2003) P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer’s disease. J Biol Chem 278:13309–13317
    Moore D, Chambers J, Waldvogel H et al (2000) Regional and cellular distribution of the P2Y1 purinergic receptor in the human brain: striking neuronal localisation. J Comp Neurol 421:374–384
    Moore D, Iritani S, Chambers J et al (2000) Immunohistochemical localization of the P2Y1 purinergic receptor in Alzheimer’s disease. Neuroreport 11:3799–3803
    Braun N, Zhu Y, Krieglstein J et al (1998) Upregulation of the enzyme chain hydrolyzing extracellular ATP after transient forebrain ischemia in the rat. J Neurosci 18:4891–4900
    Melani A, Turchi D, Vannucchi MG et al (2005) ATP extracellular concentrations are increased in the rat striatum during in vivo ischemia. Neurochem Int 47:442–448
    Phillis JW, O’Regan MH, Perkins LM et al (1993) Adenosine 5′-triphosphate release from the normoxic and hypoxic in vivo rat cerebral cortex. Neurosci Lett 151:94–96
    Juranyi Z, Sperlagh B, Vizi ES et al (1999) Involvement of P2 purinoceptors and the nitric oxide pathway in [3H]purine outflow evoked by short-term hypoxia and hypoglycemia in rat hippocampal slices. Brain Res 823:183–190
    Cavaliere F, Florenzano F, Amadio S et al (2003) Up-regulation of P2X2, P2X4 receptor and ischemic cell death: prevention by P2 antagonists. Neuroscience 120:85–98
    Cavaliere F, Amadio S, Sancesario G et al (2004) Synaptic P2X7 and oxygen/glucose deprivation in organotypic hippocampal cultures. J Cereb Blood Flow Metab 24:392–398
    Franke H, Günther A, Grosche J et al (2004) 2X7 receptor expression after ischemia in the cerebral cortex of rats. J Neuropathol Exp Neurol 63:686–699
    Kim M, Jiang LH, Wilson HL et al (2001) Proteomic and functional evidence for a P2X7 receptor signaling complex. EMBO J 2:6347–6358
    Moran-Jimenez MJ, Matute C et al (2000) Immunohistochemical localization of the P2Y1 purinergic receptor in neurons and glial cells of the central nervous system. Mol Brain Res 78:50–58
    Viscomi MT, Florenzano F, Conversi D et al (2004) Axotomy dependent purinergic and nitrergic co-expression. Neuroscience 123:393–404
    Tsuzuki K, Kondo E, Fukuoka T et al (2001) Differential regulation of P2X3 mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia. Pain 91:351–360
    Wang X, Arcuino G, Takano T et al (2004) P2X7 receptor inhibition improves recovery after spinal cord injury. Nat Med 10:821–827
    Florenzano F, Viscomi MT, Cavaliere F et al (2002) Cerebellar lesion up-regulates P2X1 and P2X2 purinergic receptors in precerebellar nuclei. Neuroscience 115:425–434
    Viscomi MT, Florenzano F, Amadio S (2005) Partial resistance of ataxin-2-containing olivary and pontine neurons to axotomy-induced degeneration. Brain Res Bull 66:212–221
    Arthur DB, Akassoglou K, Insel PA et al (2005) P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation. Proc Natl Acad Sci U S A 102:19138–19143
    Peković S, Filipovic R, Subasic S et al (2005) Downregulation of glial scarring after brain injury: the effect of purine nucleoside analogue ribavirin. Ann N Y Acad Sci 1048:296–310
    Pines A, Bivi N, Vascotto C et al (2006) Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway. J Cell Physiol 209:44–55
    Gerasimovskaya EV, Ahmad S, White CW et al (2002) Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor. J Biol Chem 277:44638–44650
    Murray AW (2004) Recycling the cell cycle: cyclins revisited. Cell 116:221–234
    Morgan DA, Class R, Soslau G et al (1997) Cytokine-mediated erythroid maturation in megakaryoblastic human cell line HU-3. Exp Hematol 25:1378–1385
    Sherr CJ, Roberts JM (2004) Living with or without cyclins and cyclin-dependent kinases. Genes Dev 18:2699–2711
    Neary JT, Kang Y, Willoughby KA et al (2003) Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors. J Neurosci 23:2348–2356
    Budagian V, Bulanova E, Brovko L et al (2003) Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B. J Biol Chem 278:1549–1560
    Ahmed-Choudhury J, Russell CL, Randhawa S et al (2003) Differential induction of nuclear factor-kappaB and activator protein-1 activity after CD40 ligation is associated with primary human hepatocyte apoptosis or intrahepatic endothelial cell proliferation. Mol Biol Cell 14:1334–1345
    Krejci P, Bryja V, Pachernik J et al (2004) FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells. Exp Cell Res 297:152–164
    Ahamed S, Foster JS, Bukovsky A et al (2001) Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells. Mol Carcinog 30:88–98
    Cordova-Alarcon E, Centeno F, Reyes-Esparza J et al (2005) Effects of HRAS oncogene on cell cycle progression in a cervical cancer-derived cell line. Arch Med Res 36:311–316
    Hideshima T, Nakamura N, Chauhan D et al (2001) Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. Oncogene 20:5991–6000
    Glauser DA, Schlegel W (2007) Sequential actions of ERK1/2 on the AP-1 transcription factor allow temporal integration of metabolic signals in pancreatic (beta) cells. FASEB J (in press)
    Chu TS, Wu MS, Wu KD et al (2007) Endothelin-1 activates MAPKs and modulates cell cycle proteins in OKP cells. J Formos Med Assoc 106:273–280
    Migliaccio A, Castoria G, Di Domenico M et al (2002) Sex steroid hormones act as growth factors. J Steroid Biochem Mol Biol 83:31–35
    Lents NH, Keenan SM, Bellone C et al (2002) Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2. J Biol Chem 277:47469–47475
    Reshetnikova G, Barkan R, Popov B et al (2000) Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein. Exp Cell Res 259:35–53
    Bhatt KV, Spofford LS, Aram G et al (2005) Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling. Oncogene 24:3459–3471
    Lefevre G, Calipel A, Mouriaux F et al (2003) Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells. Oncogene 22:8813–8822
    Delmas C, Manenti S, Boudjelal A et al (2001) The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells. J Biol Chem 276:34958–34965
    Zhang W, Lee JC, Kumar S et al (1999) ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells. J Bone Miner Res 14:528–535
    Boyer JL, Mohanram A, Camaioni E et al (1998) Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2′-deoxyadenosine 3′,5′-bisphosphate. Br J Pharmacol 124:1–3
    Baurand A, Gachet C (2003) The P2Y(1) receptor as a target for new antithrombotic drugs: a review of the P2Y(1) antagonist MRS-2179. Cardiovasc Drug Rev 21:67–76
    Ulrich H, Trujillo CA, Nery AA et al (2006) DNA and RNA aptamers: from tools for basic research towards therapeutic applications. Comb Chem High Throughput Screen 9:619–632
    Trujillo CA, Nery AA, Martins AH et al (2006) Inhibition mechanism of the recombinant rat P2X(2) receptor in glial cells by suramin and TNP-ATP. Biochemistry 45:224–233
    Trujillo CA, Majumder P, Gonzalez FA et al (2007) Immobilized P2X(2) purinergic receptor stationary phase for chromatographic determination of pharmacological properties and drug screening. J Pharm Biomed Anal 44:701–710

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