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Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRß/IRS-1 and Akt (2009)

  • Authors:
  • USP affiliated authors: CURI, RUI - ICB ; SILVEIRA, LEONARDO DOS REIS - EEFERP
  • USP Schools: ICB; EEFERP
  • DOI: 10.1007/s00125-009-1498-1
  • Subjects: FISIOLOGIA
  • Language: Inglês
  • Imprenta:
  • Source:
    • Título do periódico: Diabetologia
    • ISSN: 0012-186X
    • Volume/Número/Paginação/Ano: v. 52, n. 11, p. 2425-34, 2009
  • Acesso online ao documento

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    Informações sobre o DOI: 10.1007/s00125-009-1498-1 (Fonte: oaDOI API)
    • Este periódico é de assinatura
    • Este artigo é de acesso aberto
    • URL de acesso aberto
    • Cor do Acesso Aberto: bronze
    Informações sobre o Citescore
  • Título: Diabetologia

    ISSN: 0012-186X

    Citescore - 2017: 5.09

    SJR - 2017: 3.228

    SNIP - 2017: 1.619


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    ICB12100025044PC-ICB BMB SEP 2009
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    • ABNT

      CARVALHO-FILHO, M. A.; ROPELLE, E. R.; PAULI, R. J.; et al. Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRß/IRS-1 and Akt. Diabetologia, Berlin, v. 52, n. 11, p. 2425-34, 2009. DOI: 10.1007/s00125-009-1498-1.
    • APA

      Carvalho-Filho, M. A., Ropelle, E. R., Pauli, R. J., Cintra, D. E., Tsukumo, D. M. L., Silveira, L. R., et al. (2009). Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRß/IRS-1 and Akt. Diabetologia, 52( 11), 2425-34. doi:10.1007/s00125-009-1498-1
    • NLM

      Carvalho-Filho MA, Ropelle ER, Pauli RJ, Cintra DE, Tsukumo DML, Silveira LR, Curi R, Carvalheira JBC, Velloso LA, Saad MJA. Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRß/IRS-1 and Akt. Diabetologia. 2009 ; 52( 11): 2425-34.
    • Vancouver

      Carvalho-Filho MA, Ropelle ER, Pauli RJ, Cintra DE, Tsukumo DML, Silveira LR, Curi R, Carvalheira JBC, Velloso LA, Saad MJA. Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRß/IRS-1 and Akt. Diabetologia. 2009 ; 52( 11): 2425-34.

    Referências citadas na obra
    Sethi JK, Hotamisligil GS (1999) The role of TNF alpha in adipocyte metabolism. Semin Cell Dev Biol 10:19–29
    Hirosumi J, Tuncman G, Chang L et al (2002) A central role for JNK in obesity and insulin resistance. Nature 420:333–336
    Perreault M, Marette A (2001) Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle. Nat Med 7:1138–1143
    Yuan M, Konstantopoulos N, Lee J et al (2001) Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 293:1673–1677
    Barreiro GC, Prattali RR, Caliseo CT et al (2004) Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats. Biochem Biophys Res Commun 320:992–997
    Hundal RS, Petersen KF, Mayerson AB et al (2002) Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J Clin Invest 109:1321–1326
    Kim JK, Kim YJ, Fillmore JJ et al (2001) Prevention of fat-induced insulin resistance by salicylate. J Clin Invest 108:437–446
    Gao Z, Zuberi A, Quon MJ, Dong Z, Ye J (2003) Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases. J Biol Chem 278:24944–24950
    Carvalho-Filho MA, Ueno M, Hirabara SM et al (2005) S-nitrosylation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance. Diabetes 54:959–967
    Carvalho-Filho MA, Ueno M, Carvalheira JB, Velloso LA, Saad MJ (2006) Targeted disruption of iNOS prevents LPS-induced S-nitrosylation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice. Am J Physiol Endocrinol Metab 291:E476–E482
    Cieslik K, Zhu Y, Wu KK (2002) Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway. J Biol Chem 277:49304–49310
    Katsuyama K, Shichiri M, Kato H, Imai T, Marumo F, Hirata Y (1999) Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells. Endocrinology 140:2183–2190
    Wang Z, Brecher P (1999) Salicylate inhibition of extracellular signal-regulated kinases and inducible nitric oxide synthase. Hypertension 34:1259–1264
    Sugita H, Fujimoto M, Yasukawa T et al (2005) Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells. J Biol Chem 280:14203–14211
    Bonora E, Moghetti P, Zancanaro C et al (1989) Estimates of in vivo insulin action in man: comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp studies. J Clin Endocrinol Metab 68:374–378
    Prada PO, Zecchin HG, Gasparetti AL et al (2005) Western diet modulates insulin signaling, c-Jun N-terminal kinase activity, and insulin receptor substrate-1ser307 phosphorylation in a tissue-specific fashion. Endocrinology 146:1576–1587
    Saad MJ, Araki E, Miralpeix M, Rothenberg PL, White MF, Kahn CR (1992) Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. J Clin Invest 90:1839–1849
    Tremblay F, Lavigne C, Jacques H, Marette A (2001) Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities. Diabetes 50:1901–1910
    Jaffrey SR, Snyder SH (2001) The biotin switch method for the detection of S-nitrosylated proteins. Sci STKE 2001: PL1
    Martinez-Ruiz A, Lamas S (2004) Detection and proteomic identification of S-nitrosylated proteins in endothelial cells. Arch Biochem Biophys 423:192–199
    Lynge J, Juel C, Hellsten Y (2001) Extracellular formation and uptake of adenosine during skeletal muscle contraction in the rat: role of adenosine transporters. J Physiol 537:597–605
    Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254
    Pollock JS, Forstermann U, Mitchell JA et al (1991) Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci U S A 88:10480–10484
    Cai D, Yuan M, Frantz DF et al (2005) Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 11:183–190
    Rohl M, Pasparakis M, Baudler S et al (2004) Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance. J Clin Invest 113:474–481
    Jiang G, Dallas-Yang Q, Liu F, Moller DE, Zhang BB (2003) Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells. J Biol Chem 278:180–186
    Prattali RR, Barreiro GC, Caliseo CT et al (2005) Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals. FEBS Lett 579:3152–3158
    Fujimoto M, Shimizu N, Kunii K, Martyn JA, Ueki K, Kaneki M (2005) A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice. Diabetes 54:1340–1348
    Taylor BS, Geller DA (2000) Molecular regulation of the human inducible nitric oxide synthase (iNOS) gene. Shock 13:413–424
    Yasukawa T, Tokunaga E, Ota H, Sugita H, Martyn JA, Kaneki M (2005) S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance. J Biol Chem 280:7511–7518
    Dallaire P, Bellmann K, Laplante M et al (2008) Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes 57:1999–2011
    Fleischman A, Shoelson SE, Bernier R, Goldfine AB (2008) Salsalate improves glycemia and inflammatory parameters in obese young adults. Diabetes Care 31:289–294
    Goldfine AB, Silver R, Aldhahi W et al (2008) Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes. Clin Transl Sci 1:36–43