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Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil (2011)

  • Authors:
  • USP affiliated authors: OLIVEIRA, CLAUDIA PINTO MARQUES SOUZA DE - FM ; CARRILHO, FLAIR JOSÉ - FM
  • USP Schools: FM; FM
  • DOI: 10.1186/1475-2891-10-86
  • Subjects: POLIMORFISMO; FÍGADO GORDUROSO; GENÓTIPOS (ANÁLISE); REGIÃO NORDESTE; HEPATITE CRÔNICA; BRASIL
  • Language: Inglês
  • Imprenta:
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    Informações sobre o DOI: 10.1186/1475-2891-10-86 (Fonte: oaDOI API)
    • Este periódico é de acesso aberto
    • Este artigo é de acesso aberto
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    • Cor do Acesso Aberto: hybrid
    • Licença: cc-by
    Informações sobre o Citescore
  • Título: Nutrition Journal

    ISSN: 1475-2891

    Citescore - 2017: 3.93

    SJR - 2017: 1.447

    SNIP - 2017: 1.585


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    • ABNT

      SIQUEIRA, Erika R. F.; OLIVEIRA, Cláudia P. M. S.; MUNIZ, Maria T. C.; et al. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil. Nutrition Journal, London, v. 10, n. 86, p. 1-8 (online), 2011. Disponível em: < http://www.nutritionj.com/content/pdf/1475-2891-10-86.pdf > DOI: 10.1186/1475-2891-10-86.
    • APA

      Siqueira, E. R. F., Oliveira, C. P. M. S., Muniz, M. T. C., Silva, F., Pereira, L. M. M. B., & Carrilho, F. J. (2011). Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil. Nutrition Journal, 10( 86), 1-8 (online). doi:10.1186/1475-2891-10-86
    • NLM

      Siqueira ERF, Oliveira CPMS, Muniz MTC, Silva F, Pereira LMMB, Carrilho FJ. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil [Internet]. Nutrition Journal. 2011 ; 10( 86): 1-8 (online).Available from: http://www.nutritionj.com/content/pdf/1475-2891-10-86.pdf
    • Vancouver

      Siqueira ERF, Oliveira CPMS, Muniz MTC, Silva F, Pereira LMMB, Carrilho FJ. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil [Internet]. Nutrition Journal. 2011 ; 10( 86): 1-8 (online).Available from: http://www.nutritionj.com/content/pdf/1475-2891-10-86.pdf

    Referências citadas na obra
    Refsun H, Ueland P, Nygard O, Vollset SE: Homocysteine and cardiovascular disease. Annu Rev Med. 1998, 31-62. 49
    Bostom AG, Lathrop L: Hyperhomocysteinemia in end-stage renal disease: Prevalence, etiology, and potential relationship to arteriosclerosis outcomes. Kidney Int. 1997, 52: 10-20. 10.1038/ki.1997.298.
    Eskes TKAB: Open or closed? A word of differences: A history of homocysteine research. Nutr Rev. 1998, 56: 236-244.
    Lehmann M, Gottfries CG, Regland B: Identification of cognitive impairment in the elderly: Homocysteine is an early marker. Dementia. 1999, 10: 12-20.
    Ji C, Kaplowitz N: Betaine decreases hyperyhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. Gastroenterology. 2003, 124: 1488-1499. 10.1016/S0016-5085(03)00276-2.
    Goyette P, Sumner JS, Milos R, Duncan AM, Rosenblatt DS, Matthews RG, Rozen R: Human methylenetetrahydro folate reductase: isolation of cDNA, mapping and mutation identification. Nat Gen. 1994, 7: 195-200. 10.1038/ng0694-195.
    Van der Put NMJ, Gabreels F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK, van den Heuvel LP, Blom HJ: A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?. Am J HumGenet. 1998, 62: 1044-1051. 10.1086/301825.
    Andreassi MG, Botto N, Battaglia D, Antonioli E, Masetti S, Manfredi S, Colombo MG, Biagini A, Clerico A: Methylenetetrahydro folate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease. HumGenet. 2003, 112: 171-177.
    Rozen R: Polymorphisms of folate and cobalamin metabolism. Edited by: Carmel R, Jacobsen DW. 2001, Homocysteine in Health and Disease. UK: Cambridge University Press, 259-270.
    Adinolfi LE, Ingrosso D, Cesaro G, Cimmino A, D'Antò M, Capasso R, Zappia V, Ruggiero G: Hyperhomocysteinemia and the MTHFR C677T polymorphism promote steatosis and fibrosis in chronic hepatitis C patients. Hepatology. 2005, 41: 995-1003. 10.1002/hep.20664.
    Finelli L, Alter MJ: Global epidemiology of hepatitis C virus infection. Lancet Infect Dis. 2005, 5: 558-56.7. 10.1016/S1473-3099(05)70216-4.
    Negro F, Sanyal AJ: Hepatitis C virus, steatosis and lipid abnormalities: clinical and pathogenic data. Liver Int. 2009, Suppl 2, 26-37. 29
    Fiore G, Fera G, Napoli N, Vella F, Schiraldi O: Liver steatosis and chronic hepatitis C: a spurious association?. Eur J Gastroenterol Hepatol. 1996, 8: 125e129-
    Patton HM, Patel K, Behling C, Bylund D, Blatt LM, Vallee M, Heaton S, Conrad A, Pockros PJ, McHutchison JG: The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients. J Hepatol. 2004, 40: 484-490.
    Rubbia-Brandt L, Fabris P, Paganin S, Leandro G, Male PJ, Giostra E, Carlotto A, Bozzola L, Smedile A, Negro F: Steatosis affects chronic hepatitisC progression in a genotype specific way. Gut. 2004, 53: 406-12. 10.1136/gut.2003.018770.
    Castera L, Hezode C, Roudot-Thoraval F, Lonjon I, Zafrani ES, Pawlotsky JM, Dhumeaux D: Effect of antiviral treatment on evolution of liver steatosis in patients with chronic hepatitis C: indirect evidence of a role of hepatitis C virus genotype 3 in steatosis. Gut. 2004, 53: 420-4. 10.1136/gut.2002.009936.
    Hezode C, Roudot-Thoraval F, Zafrani ES, Dhumeaux D, Pawlotsky JM: Different mechanisms of steatosis in hepatitis C virus genotypes 1 and 3 infections. J Viral Hepat. 2004, 11: 455-8. 10.1111/j.1365-2893.2004.00528.x.
    Gruady SM, Hansen B, Smith SC, Cleeman JI, Kahn RA: Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation. 2004, 109: 551-6. 10.1161/01.CIR.0000112379.88385.67.
    Matthews DR, Hosker JP, Rudesnki AS, Naylor BA, Treacher DF, Turner RC: Homeostasis model assessment: insulin resistance and β-cell function from plasma fasting blood sugar and insulin concentration in man. Diabetologia. 1985, 28: 412-419. 10.1007/BF00280883.
    Mindicino HJ, Carlsen J, Tewari P, Aagaard O, Zhang B, Conarpe C: An evaluation of an automated homocysteine method on the Bayer ADVIA Centaur automated chemiluminescent system. Clin Lab. 2002, 48: 493-496.
    Friedewald WT, Levi RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein in plasma, without the use of preparative ultracentrifuge. Clin Chem. 1992, 21: 1983-1985.
    Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, van den Heuvel LP, et al: A candidate genetic risk factor for vascular disease: A common mutation at the methylenetetrahydrofolate reductase locus. Nature Gen. 1995, 10 (1): 111-113. 10.1038/ng0595-111.
    Almawi WY, Ameen G, Tamim H, Finan RR, Irani-Hakime N: Factor V G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677T gene polymorphism in angiographically documented coronary artery disease. J Thromb Thrombolysis. 2004, 17: 199-205.
    Morita H, Taguchi J, Kurihara H, Kitaoka M, Kaneda H, Kurihara Y, Maemura K, Shindo T, Minamino T, Ohno M, Yamaoki K, Ogasawara K, Aizawa T, Suzuki S, Yazaki Y: Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease. Circulation. 1997, 95: 2032-2036.
    Jee SH, Beaty TH, Suh I, Yoon Y, Appel LJ: The methylenetetrahydrofolate reductase gene is associated with increased cardiovascular risk in Japan, but not in other populations. Atherosclerosis. 2000, 153: 161-168. 10.1016/S0021-9150(00)00389-0.
    Toniutto P, Fabris C, Falleti E, Cussigh A, Fontanini E, Bitetto D, Fornasiere E, Minisini R, De Feo T, Marangoni F, Pirisi M: Methylenetetrahydrofolate reductase C677T polymorphismand liver fibrosis progression in patients with recurrent hepatitis C. Liver International. 2007, 273-263.
    Borgia G, Gentile I, Fortunato G, Borrelli F, Borelli S, de Caterina M, Di Taranto MD, Simone M, Borgia F, Viola C, Reynaud L, Cerini R, Sacchetti L: Homocysteine levels and sustained virological response to pegylatedinterferon α2b plus ribavirin therapy for chronic hepatitis C:a prospective study. Liver International. 2008, 248-252.
    da Silva VC, Ramos FJ, Freitas EM, de Brito-Marques PR, Cavalcanti MN, D'Almeida V, Cabral-Filho JE, Muniz MT: Alheimer's Disease in Brazilian Elderly has a Relation With Homocysteine but not with MTHFR polymorphisms. Arq Neuropsiquiatr. 2006, 64 (4): 941-945. 10.1590/S0004-282X2006000600010.
    Couto FD, Adorno EV, Menezes JF, MouraNeto JP, dos Reis MG: C677T polymorphism of the MTHFR gene and variant haemoglobin: a study in newborns from Salvador,Bahia, Brazil. Cad Saude Publica. 2004, 20 (2): 529-533. 10.1590/S0102-311X2004000200021.
    Lonardo A, Adinolfi LE, Loria P, Carulli N, Ruggiero G, Day CP: Steatosis and hepatitis C: mechanisms and significance for hepatic and extrahepatic disease. Gastroenterology. 2004, 126: 586-597. 10.1053/j.gastro.2003.11.020.
    Graham IM, Daly LE, Refsum HM, Robinson K, Brattström LE, Ueland PM, Palma-Reis RJ, Boers GH, Sheahan RG, Israelsson B, Uiterwaal CS, Meleady R, McMaster D, Verhoef P, Witteman J, Rubba P, Bellet H, Wautrecht JC, de Valk HW, Sales Lúis AC, Parrot-Rouland FM, Tan KS, Higgins I, Garcon D, Andria G, et al: Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA. 1997, 277: 1775-81. 10.1001/jama.277.22.1775.
    Clarke R, Daly L, Robinson K, Naughten E, Cahalane S, Fowler B, Graham I: Hyperhomocysteinemia: an independent risk factor for vascular disease. N Engl J Med. 1991, 324: 1149-55. 10.1056/NEJM199104253241701.
    Den Heijer M, Rosendaal FR, Blom HJ, Gerrits WB, Bos GM: Hyperhomocysteinemia and venous thrombosis: a metaanalysis. Thromb Haemost. 1998, 80: 874-7.
    Cattaneo M: Hyperhomocysteinemia, atherosclerosis and thrombosis. Thromb Haemost. 1999, 81: 165-76.
    Melvin Hayden R, Suresh Tyagi C: Homocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: The pleiotropic effects of folate supplementation. Nutrition Journal. 2004, 3: 4-10.1186/1475-2891-3-4.
    Garcia-Tevijano ER, Berasain C, Rodriguez JA, Corrales FJ, Arias R, Martín-Duce A, Caballería J, Mato JM, Avila MA: Hyperhomocysteinemia in liver cirrhosis: mechanisms and role in vascular and hepatic fibrosis. Hypertension. 2001, 38: 1217-21. 10.1161/hy1101.099499.
    Torres L, Garcia-Trevijano E R, Rodriguez JA, Carretero MV, Bustos M, Fernández E, Eguinoa E, Mato JM, Avila MA: Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis. Biochim Biophys Acta. 1999, 1455: 12-22.
    Kang SS, Zhou J, Wong PW, Kowalisyn J, Strokosch G: Intermediate homocysteinemia:a thermolabile variant of methylenetetrahydrofolate reductase. AmJ Hum Genet. 1988, 43: 414-421.
    Finkelstein JD, Martin JJ, Harris BJ: Methionine metabolism in mammals. The methionine-sparing effect of cystine. J Biol Chem. 1988, 263: 11750-11754.
    Upchurch GR, Welch GN, Fabian AJ, Freedman JE, Johnson JL, Keaney JF, Loscalzo J: Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase. JBiol Chem. 1997, 272: 17012-17017. 10.1074/jbc.272.27.17012.
    Outinen PA, Sood SK, Liaw PC, Sarge KD, Maeda N, Hirsh J, Ribau J, Podor TJ, Weitz JI, Austin RC: Characterization of the stress-inducing effects of homocysteine. Biochem J. 1998, 332: 213-221.
    Dayal S, Brown KL, Weydert CJ, Oberley LW, Arning E, Bottiglieri T, Faraci FM, Lentz SR: Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction. Arterioscler Thromb Vasc Biol. 2002, 22: 1996-2002. 10.1161/01.ATV.0000041629.92741.DC.
    Yla-Herttuala S, Palinski W, Rosenfeld ME, Parthasarathy S, Carew TE, Butler S, Witztum JL, Steinberg D: Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit andman. J Clin Invest. 1989, 84: 1086-1095. 10.1172/JCI114271.
    Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, Austin RC: Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest. 2001, 107: 1263-73. 10.1172/JCI11596.
    Andre P, Komurian-Pradel F, Deforges S, Perret M, Berland JL, Sodoyer M, Pol S, Bréchot C, Paranhos-Baccalà G, Lotteau V: Characterization of low- and very-low-density hepatitis C virus RNA-containing particles. J Virol. 2002, 76: 6919-6928. 10.1128/JVI.76.14.6919-6928.2002.
    Agnello V, Abel G, Elfahal M, Knight GB, Zhang QX: Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. Proc Natl Acad Sci USA. 1999, 96: 12766-12771. 10.1073/pnas.96.22.12766.
    Molina S, Castet V, Fournier-Wirth C, Pichard-Garcia L, Avner R, Harats D, Roitelman J, Barbaras R, Graber P, Ghersa P, Smolarsky M, Funaro A, Malavasi F, Larrey D, Coste J, Fabre JM, Sa-Cunha A, Maurel P: The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus. J Hepatol. 2007, 46: 411-419. 10.1016/j.jhep.2006.09.024.