Ver registro no DEDALUS
Exportar registro bibliográfico

Metrics


Metrics:

Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice (2015)

  • Authors:
  • USP affiliated authors: SILVEIRA, LEONARDO DOS REIS - EEFERP ; KETTELHUT, ISIS DO CARMO - FMRP
  • USP Schools: EEFERP; FMRP
  • DOI: 10.1007/s00726-014-1903-z
  • Subjects: HOMEOSTASE; TREINAMENTO FÍSICO; PROTEÍNAS; GLICOSE; MÚSCULO ESQUELÉTICO
  • Language: Inglês
  • Imprenta:
    • Publisher place: Wien
    • Date published: 2015
  • Source:
    • Título do periódico: Amino Acids
    • ISSN: 0939-4451
    • Volume/Número/Paginação/Ano: v. 47, n. 4, p. 745-755, 2015
  • Acesso online ao documento

    Online accessDOI or search this record in
    Informações sobre o DOI: 10.1007/s00726-014-1903-z (Fonte: oaDOI API)
    • Este periódico é de assinatura
    • Este artigo NÃO é de acesso aberto
    • Cor do Acesso Aberto: closed
    Versões disponíveis em Acesso Aberto do: 10.1007/s00726-014-1903-z (Fonte: Unpaywall API)

    Título do periódico: Amino Acids

    ISSN: 0939-4451,1438-2199



      Não possui versão em Acesso aberto
    Informações sobre o Citescore
  • Título: Amino Acids

    ISSN: 0939-4451

    Citescore - 2017: 2.94

    SJR - 2017: 1.135

    SNIP - 2017: 0.989


  • Exemplares físicos disponíveis nas Bibliotecas da USP
    BibliotecaCód. de barrasNúm. de chamada
    FMRP2762862pcd 2762862 Estantes Deslizantes
    How to cite
    A citação é gerada automaticamente e pode não estar totalmente de acordo com as normas

    • ABNT

      COSTA-JÚNIOR, José M.; ROSA, Morgana R.; PROTZEK, André O. P.; et al. Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice. Amino Acids, Wien, v. 47, n. 4, p. 745-755, 2015. Disponível em: < http://dx.doi.org/10.1007/s00726-014-1903-z > DOI: 10.1007/s00726-014-1903-z.
    • APA

      Costa-Júnior, J. M., Rosa, M. R., Protzek, A. O. P., Paula, F. M., Ferreira, S. M., Rezende, L. F., et al. (2015). Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice. Amino Acids, 47( 4), 745-755. doi:10.1007/s00726-014-1903-z
    • NLM

      Costa-Júnior JM, Rosa MR, Protzek AOP, Paula FM, Ferreira SM, Rezende LF, Vanzela EC, Zoppi CC, Silveira L dos R, Kettelhut I do C, Boschero AC, Oliveira CAM, Carneiro EM. Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice [Internet]. Amino Acids. 2015 ; 47( 4): 745-755.Available from: http://dx.doi.org/10.1007/s00726-014-1903-z
    • Vancouver

      Costa-Júnior JM, Rosa MR, Protzek AOP, Paula FM, Ferreira SM, Rezende LF, Vanzela EC, Zoppi CC, Silveira L dos R, Kettelhut I do C, Boschero AC, Oliveira CAM, Carneiro EM. Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice [Internet]. Amino Acids. 2015 ; 47( 4): 745-755.Available from: http://dx.doi.org/10.1007/s00726-014-1903-z

    Referências citadas na obra
    Baar K, Nader G, Bodine S (2006) Resistance exercise, muscle loading/unloading and the control of muscle mass. Essays Biochem 42:61–74
    Bajotto G, Sato Y, Kitaura Y, Shimomura Y (2011) Effect of branched-chain amino acid supplementation during unloading on regulatory components of protein synthesis in atrophied soleus muscles. Eur J Appl Physiol 111:1815–1828
    Bidlingmeyer BA, Cohen SA, Tarvin TL (1984) Rapid analysis of amino acids using pre-column derivatization. J Chromatogr 336:93–104
    Baptista IL, Leal ML, Artioli GG, Aoki MS, Fiamoncini J, Turri AO, Curi R, Miyabara EH, Moriscot AS (2010) Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases. Muscle Nerve 41:800–808
    Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ (2001) Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294:1704–1708
    Brault JJ, Jespersen JG, Goldberg AL (2010) Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy. J Biol Chem 285:19460–19471
    Chan AY, Dyck JR (2005) Activation of AMP-activated protein kinase (AMPK) inhibits protein synthesis: a potential strategy to prevent the development of cardiac hypertrophy. Can J Physiol Pharmacol 83:24–28
    Dreyer HC, Drummond MJ, Pennings B, Fujita S, Glynn EL, Chinkes DL, Dhanani S, Volpi E, Rasmussen BB (2008) Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. Am J Physiol Endocrinol Metab 294:E392–E400
    Gobatto CA, Manchado-Gobatto FB, Carneiro LG, Araujo GG, Reis IGM (2009) Maximal lactate steady state for aerobic evaluation of swimming mice. Comp Exerc Physiol 3:99–103
    Hardie DG (2011) AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Genes Dev 25:1895–1908
    Hussain S, Foreman O, Perkins SL, Witzig TE, Miles RR, van Deursen J, Galardy PJ (2010) The de-ubiquitinase UCH-L1 is an oncogene that drives the development of lymphoma in vivo by deregulating PHLPP1 and Akt signaling. Leukemia 24:1641–1655
    Jewell JL, Guan KL (2013) Nutrient signaling to mTOR and cell growth. Trends Biochem Sci 38:233–242
    Kim HJ, Kim YM, Lim S, Nam YK, Jeong J, Lee KJ (2009) Ubiquitin C-terminal hydrolase-L1 is a key regulator of tumor cell invasion and metastasis. Oncogene 28:117–127
    Krebs M, Brunmair B, Brehm A, Artwohl M, Szendroedi J, Nowotny P, Roth E, Fürnsinn C, Promintzer M, Anderwald C, Bischof M, Roden M (2007) The mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man. Diabetes 56:1600–1607
    Lira VA, Benton CR, Yan Z, Bonen A (2010) PGC-1alpha regulation by exercise training and its influences on muscle function and insulin sensitivity. Am J Physiol Endocrinol Metab 299:E145–E161
    Maarbjerg SJ, Sylow L, Richter EA (2011) Current understanding of increased insulin sensitivity after exercise—emerging candidates. Acta Physiol 202:323–335
    Macotela Y, Emanuelli B, Bång AM, Espinoza DO, Boucher J, Beebe K, Gall W, Kahn CR (2011) Dietary leucine–an environmental modifier of insulin resistance acting on multiple levels of metabolism. PLoS ONE 6:e21187
    Nader GA (2006) Concurrent strength and endurance training: from molecules to man. Med Sci Sports Exerc 38:1965–1970
    Nicastro H, Artioli GG, Costa AdoS S, Solis MY, da Luz CR, Blachier F, Lancha AH (2011) An overview of the therapeutic effects of leucine supplementation on skeletal muscle under atrophic conditions. Amino Acids 40:287–300
    O’Neill HM, Maarbjerg SJ, Crane JD, Jeppesen J, Jørgensen SB, Schertzer JD, Shyroka O, Kiens B, van Denderen BJ, Tarnopolsky MA, Kemp BE, Richter EA, Steinberg GR (2011) AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise. Proc Natl Acad Sci USA 108:16092–16097
    O’Neill HM (2013) AMPK and exercise: glucose uptake and insulin sensitivity. Diabetes Metab J 37:1–21
    Peters SJ, van Helvoort A, Kegler D, Argilès JM, Luiking YC, Laviano A, van Bergenhenegouwen J, Deutz NE, Haagsman HP, Gorselink M, van Norren K (2011) Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice. Oncol Rep 26:247–254
    Rezende EL, Garland T, Chappell MA, Malisch JL, Gomes FR (2006) Maximum aerobic performance in lines of Mus selected for high wheel-running activity: effects of selection, oxygen availability and the mini-muscle phenotype. J Exp Biol 209:115–127
    Ruderman NB, Carling D, Prentki M, Cacicedo JM (2013) AMPK, insulin resistance, and the metabolic syndrome. J Clin Invest 123:2764–2772
    Saha AK, Xu XJ, Lawson E, Deoliveira R, Brandon AE, Kraegen EW, Ruderman NB (2010) Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. Diabetes 59:2426–2434
    Salomão EM, Gomes-Marcondes MC (2012) Light aerobic physical exercise in combination with leucine and/or glutamine-rich diet can improve the body composition and muscle protein metabolism in young tumor-bearing rats. J Physiol Biochem 68:493–501
    Salomão EM, Toneto AT, Silva GO, Gomes-Marcondes MC (2010) Physical exercise and a leucine-rich diet modulate the muscle protein metabolism in Walker tumor-bearing rats. Nutr Cancer 62:1095–1104
    Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117:399–412
    Sandri M, Lin J, Handschin C, Yang W, Arany ZP, Lecker SH, Goldberg AL, Spiegelman BM (2006) PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci USA 103:16260–16265
    Scharff R, Wool IG (1966) Effect of diabetes on the concentration of amino acids in plasma and heart muscle of rats. Biochem J 99(1):173–178
    Tischler ME, Desautels M, Goldberg AL (1982) Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? J Biol Chem 257:1613–1621
    Tong JF, Yan X, Zhu MJ, Du M (2009) AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes. J Cell Biochem 108:458–468
    Waalkes TP, Udenfriend S (1957) A fluorometric method for the estimation of tyrosine in plasma and tissues. J Lab Clin Med 50:733–736
    Wilkinson SB, Phillips SM, Atherton PJ, Patel R, Yarasheski KE, Tarnopolsky MA, Rennie MJ (2008) Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle. J Physiol 586:3701–3717