Exfoliative citology as acomplementary tool for oral diagnosis: cost-effectiveness or time lost? (2019)
- Authors:
- Autor USP: SOUSA, SUZANA CANTANHEDE ORSINI MACHADO DE - FO
- Unidade: FO
- Subjects: CITOLOGIA EXFOLIATIVA; DIAGNÓSTICO BUCAL
- Language: Inglês
- Abstract: Objective To analyze the cytological diagnosis and compare with the clinical provisional diagnosis to determine the sensitivity and specificity of exfoliative cytology in oral lesions. Findings We retrieved 1,000 consecutive diagnosis from the cytology diagnosis files of the Oral Pathology Service at the University of São Paulo, comprising 621 females patients and 379 males patients with a median age of 53yo (range: 3-91). Regarding race, 676 patients were caucasians and 181 blacks. The most frequent sites where material was collected were tongue (n=267), palate (n=261), buccal mucosa (n=149) and gingiva (n=55). The most frequent clinical suspicion was a search for fungus (n=330) and candidiasis (n=276). Concerning the final cytological diagnosis, 25/330 cases aiming for fungus search came out as candidiasis. In those 276 cases that had candidiasis as clinical hypothesis, only 66 resulted positive for the fungus. In the 20 samples where herpes simplex was the clinical suspicion, the cytological diagnosis of herpes was confirmed in 5 cases (all classified as class II of Papanicolaou), for the remaining 15 cases only a Papanicolaou class was attributed, being 4 cases class I and 10 class II and 1 case could not be analyzed. In 15 cases there was a suspicion of squamous cell carcinoma, and of these, 4/15 were classified as class V and 2 as class 4. The remaining were 6 class II and 3 class III. Other diagnosis did not show a pattern of cytological characteristics matching the clinical suspicion. Conclusions We conclude that exfoliative cytology is mostly not helpful for diagnosis in Oral Pathology, and, biopsy remains the gold standard, unless the patient refuses a biopsy
- Imprenta:
- Publisher: Elsevier BV
- Publisher place: Amsterdam
- Date published: 2019
- Source:
- Título do periódico: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
- ISSN: 2212-4411
- Volume/Número/Paginação/Ano: v. 128, n. 1, p. e36, 2019
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ABNT
CORACIN, Fabio et al. Exfoliative citology as acomplementary tool for oral diagnosis: cost-effectiveness or time lost?. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. Amsterdam: Elsevier BV. . Acesso em: 20 abr. 2024. , 2019 -
APA
Coracin, F., Mendes, A. T., Kean, H. G., & Sousa, S. C. O. M. de. (2019). Exfoliative citology as acomplementary tool for oral diagnosis: cost-effectiveness or time lost? Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. Amsterdam: Elsevier BV. -
NLM
Coracin F, Mendes AT, Kean HG, Sousa SCOM de. Exfoliative citology as acomplementary tool for oral diagnosis: cost-effectiveness or time lost? Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2019 ; 128( 1): e36.[citado 2024 abr. 20 ] -
Vancouver
Coracin F, Mendes AT, Kean HG, Sousa SCOM de. Exfoliative citology as acomplementary tool for oral diagnosis: cost-effectiveness or time lost? Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2019 ; 128( 1): e36.[citado 2024 abr. 20 ] - A comparison between immunohistochemical profiles of odontogenic myxoma and developing human germ
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