Structure-based and molecular modeling studies for the discovery of cyclic imides as reversible cruzain inhibitors with potent anti-Trypanosoma cruzi activity (2019)
- Authors:
- Ferreira, Rafael A. A. - Universidade Estadual de Campinas (UNICAMP)
- Pauli, Ivani
- Sampaio, Thiago S. - Universidade Estadual de Campinas (UNICAMP)
- Souza, Mariana Laureano de
- Ferreira, Leonardo Luiz Gomes
- Magalhães, Luma Godoy
- Rezende Junior, Celso O. - Universidade Estadual de Campinas (UNICAMP)
- Ferreira, Rafaela S. - Universidade Federal de Minas Gerais (UFMG)
- Andricopulo, Renata Krogh
- Dias, Luiz C. - Universidade Estadual de Campinas (UNICAMP)
- Andricopulo, Adriano Defini
- USP affiliated authors: ANDRICOPULO, RENATA KROGH - IFSC ; ANDRICOPULO, ADRIANO DEFINI - IFSC ; PAULI, IVANÍ - IFSC ; SOUZA, MARIANA LAUREANO DE - IFSC ; FERREIRA, LEONARDO LUIZ GOMES - IFSC ; MAGALHÃES, LUMA GODOY - IFSC
- Unidade: IFSC
- DOI: 10.3389/fchem.2019.00798
- Subjects: DOENÇA DE CHAGAS; TRYPANOSOMA CRUZI; PLANEJAMENTO DE FÁRMACOS
- Keywords: Chagas disease; Trypanosoma cruzi; Cruzain; SAR; Medicinal chemistry; Synthesis; Inhibitors; Molecular docking
- Agências de fomento:
- Language: Inglês
- Imprenta:
- Source:
- Título do periódico: Frontiers in Chemistry
- ISSN: 2296-2646
- Volume/Número/Paginação/Ano: v. 7, p. 798-1-798-21, Nov. 2019
- Este periódico é de acesso aberto
- Este artigo é de acesso aberto
- URL de acesso aberto
- Cor do Acesso Aberto: gold
- Licença: cc-by
-
ABNT
FERREIRA, Rafael A. A. et al. Structure-based and molecular modeling studies for the discovery of cyclic imides as reversible cruzain inhibitors with potent anti-Trypanosoma cruzi activity. Frontiers in Chemistry, v. No 2019, p. 798-1-798-21, 2019Tradução . . Disponível em: https://doi.org/10.3389/fchem.2019.00798. Acesso em: 02 jun. 2024. -
APA
Ferreira, R. A. A., Pauli, I., Sampaio, T. S., Souza, M. L. de, Ferreira, L. L. G., Magalhães, L. G., et al. (2019). Structure-based and molecular modeling studies for the discovery of cyclic imides as reversible cruzain inhibitors with potent anti-Trypanosoma cruzi activity. Frontiers in Chemistry, No 2019, 798-1-798-21. doi:10.3389/fchem.2019.00798 -
NLM
Ferreira RAA, Pauli I, Sampaio TS, Souza ML de, Ferreira LLG, Magalhães LG, Rezende Junior CO, Ferreira RS, Andricopulo RK, Dias LC, Andricopulo AD. Structure-based and molecular modeling studies for the discovery of cyclic imides as reversible cruzain inhibitors with potent anti-Trypanosoma cruzi activity [Internet]. Frontiers in Chemistry. 2019 ; No 2019 798-1-798-21.[citado 2024 jun. 02 ] Available from: https://doi.org/10.3389/fchem.2019.00798 -
Vancouver
Ferreira RAA, Pauli I, Sampaio TS, Souza ML de, Ferreira LLG, Magalhães LG, Rezende Junior CO, Ferreira RS, Andricopulo RK, Dias LC, Andricopulo AD. Structure-based and molecular modeling studies for the discovery of cyclic imides as reversible cruzain inhibitors with potent anti-Trypanosoma cruzi activity [Internet]. Frontiers in Chemistry. 2019 ; No 2019 798-1-798-21.[citado 2024 jun. 02 ] Available from: https://doi.org/10.3389/fchem.2019.00798 - Multiparameter optimization of Trypanocidal cruzain inhibitors with in vivo activity and favorable pharmacokinetics
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- Chalcones and their B-aryl analogues as myeloperoxidase inhibitors: in silico, in vitro and ex vivo investigations
- QSAR and molecular docking for a series of inhibitors of the enzyme cruzain from Trypanosoma cruzi
- Chemoinformatics studies on a series of imidazoles as cruzain inhibitors
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Informações sobre o DOI: 10.3389/fchem.2019.00798 (Fonte: oaDOI API)
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